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32619 para

32619

para

paralytic

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition paralytic

研究结论

Date Results Publications
2019-12-21 10:41:00 Loss of paralytic (para), the sole gene that encodes Drosophila voltage-gated sodium channels, reduces neuroblast progeny cell number 31753914
2017-11-04 10:38:00 Study identified Shu, a Drosophila mutation causing severe behavioral defects, as a novel hypermorphic allele of the Nav channel gene para. Results suggest that the Shu Nav channels cause an increase in sodium currents, and that this defect is compensated by reduced para function, leading to a more balanced neuronal output. 27844061
2014-12-20 12:51:00 analysis revealed that 2 variant-specific amino acid changes, I260T in the S4-S5 linker of domain I (ILS4-S5) and A1731V in the voltage sensor S4 of domain IV (IVS4), contribute to the persistent sodium current (INaP) 24662849
2014-11-22 11:50:00 Trp404 and His405 as a putative point of Av3 interaction with DmNav1. 25055135
2014-03-22 12:16:00 The para(bss1) has not responded to seizure suppressor mutations identified in screens based on the Drosophila mutants eas protein and sda protein. 23797108

名称对应

Type IDs
Synonymous CG9907, DmNa[[V]], DmNa[[v]], DmNa[[v]]1, DmNav, DmNav1, Dmel\CG9907, Nav1, Ocd, Shu, Shudderer, bas, bss, l(1)14Da, l(1)ESHS48, lincRNA.S9469, olfD, par, sbl, sbl-1
Gene
UniProtKB-ID: SCNA_DROME, M9MS66_DROME, M9MSP5_DROME, M9MSP1_DROME, M9MSE7_DROME, M9MS73_DROME, M9MSE0_DROME, M9MSD8_DROME, M9MSA4_DROME, M9MSP3_DROME, M9MS84_DROME, M9MSD5_DROME, M9MSP4_DROME, M9MSP8_DROME, M9MS61_DROME, M9MS99_DROME, M9MSC3_DROME, M9MSP6_DROME, M9MS88_DROME, M9MS69_DROME, M9MSE9_DROME, M9MSP2_DROME, M9MSF2_DROME, M9MSB8_DROME, M9MSP7_DROME, M9MS75_DROME, M9MS91_DROME, M9MSA3_DROME, M9MSC7_DROME, M9MS78_DROME, M9MSD2_DROME, M9MS92_DROME, X2JKQ0_DROME, X2JFE8_DROME, M9MSQ0_DROME, M9MSF1_DROME, M9MSD7_DROME, M9PJP5_DROME, B7Z0Z2_DROME, M9MSE2_DROME, M9MSP9_DROME, M9MSB4_DROME, M9MSE4_DROME, M9MS65_DROME, M9MSE3_DROME, M9MSE6_DROME, M9MS95_DROME, M9MS87_DROME, M9MS71_DROME, M9MSE1_DROME, M9MS79_DROME, M9MSD9_DROME, M9MS83_DROME, M9MSD6_DROME, M9MSA0_DROME, M9MS96_DROME
UniprotKB: P35500, M9MS66, M9MSP5, M9MSP1, M9MSE7, M9MS73, M9MSE0, M9MSD8, M9MSA4, M9MSP3, M9MS84, M9MSD5, M9MSP4, M9MSP8, M9MS61, M9MS99, M9MSC3, M9MSP6, M9MS88, M9MS69, M9MSE9, M9MSP2, M9MSF2, M9MSB8, M9MSP7, M9MS75, M9MS91, M9MSA3, M9MSC7, M9MS78, M9MSD2, M9MS92, X2JKQ0, X2JFE8, M9MSQ0, M9MSF1, M9MSD7, M9PJP5, B7Z0Z2, M9MSE2, M9MSP9, M9MSB4, M9MSE4, M9MS65, M9MSE3, M9MSE6, M9MS95, M9MS87, M9MS71, M9MSE1, M9MS79, M9MSD9, M9MS83, M9MSD6, M9MSA0, M9MS96
UniParc: UPI0001F7700B, UPI0001F77019, UPI0001F7701B, UPI0001F77005, UPI0001F77025, UPI0001F77004, UPI0001F7700D, UPI00000072D1, UPI000153BFC9, UPI0001F77065, UPI0002944590, UPI0001F77064, UPI0001F77068, UPI0001F77071, UPI0001F77060, UPI0003E2C7D1, UPI0001F77027, UPI0001F7706C, UPI0000DD5D73, UPI0001F7702E, UPI0001F77006, UPI0001F7705A, UPI000153BFCA, UPI0001F77026, UPI0001F77024, UPI0001F77069, UPI0001F7706F, UPI0001F77023, UPI0000DD5D74, UPI0001F77015, UPI000153BFC7, UPI0001F77018, UPI0001F7702C, UPI0001F7700A, UPI0001F7706D, UPI0001F7706E, UPI0001F7706B, UPI0001914A58, UPI0001F77002, UPI000153BFC6, UPI0001F7700F, UPI0001F77003, UPI0001F77007, UPI0001F77016, UPI0001F77014, UPI0001F77021, UPI0001F7701A, UPI0001F77017, UPI0001F77061, UPI0001F7700E, UPI000153BFC8, UPI0001F7700C, UPI0001F77022, UPI0001F77063, UPI000153BFCB, UPI0001F77059, UPI0001F77070, UPI0001F77058, UPI0001F77062, UPI0001F7706A, UPI0001F7702D, UPI0001F7705B
EMBL: U26713, U26715, U26717, AE014298, U26716, U26714, M32078, AB035812, AB008113
EnsemblGenome: FBgn0285944
KO: dme:Dmel_CG9907
Nucleutide sequences
EMBL-CDS: AAF48617.2, AAB59190.1, ABI30985.1, AAB59194.1, AAB59191.1, AAA98544.1, BAA88526.1, AAA98541.1, AAA98542.1, AAB59193.1, AAA98548.1, AAA98549.1, AAA98547.1, AAA98543.1, AAB59192.1, AAB59195.1, AAA98545.1, BAA22890.1, ABI30986.1, AAA98546.1, ADV37714.1, ADV37685.1, ADV37704.1, ADV37706.1, ADV37686.1, ADV37718.1, ADV37695.1, ADV37698.1, ADV37693.1, ADV37732.1, ADV37696.1, ADV37707.1, ADV37683.1, ADV37701.1, ADV37721.1, ADV37682.1, ADV37725.1, ADV37694.1, ADV37711.1, ADV37712.1, ADV37690.1, ADV37723.1, ADV37691.1, ADV37733.1, ADV37689.1, ADV37716.1, ADV37697.1, ADV37715.1, ADV37730.1, ADV37699.1, ADV37700.1, ADV37709.1, ADV37717.1, AHN59802.1, AHN59803.1, ADV37731.1, ADV37728.1, ADV37688.1, AGB95461.1, ACL82937.1, ADV37703.1, ADV37726.1, ADV37684.1, ADV37708.1, ADV37687.1, ADV37734.1, ADV37713.1, ADV37720.1, ADV37710.1, ADV37692.1, ADV37729.1, ADV37702.1, ADV37724.1, ADV37705.1, ADV37719.1, ADV37727.1, ADV37722.1
Gene_ORFName: CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, Dmel_CG9907, CG9907, CG9907, Dmel_CG9907, Dmel_CG9907, CG9907
EnsemblGenome_TRS: FBtr0303671, FBtr0111023, FBtr0111022, FBtr0074298, FBtr0342746, FBtr0303687, FBtr0303658, FBtr0303677, FBtr0303679, FBtr0303659, FBtr0303691, FBtr0303668, FBtr0303671, FBtr0303666, FBtr0303705, FBtr0303669, FBtr0303680, FBtr0303656, FBtr0303674, FBtr0303694, FBtr0303655, FBtr0303698, FBtr0303667, FBtr0303684, FBtr0303685, FBtr0303663, FBtr0303696, FBtr0303664, FBtr0303706, FBtr0303662, FBtr0303689, FBtr0303670, FBtr0303688, FBtr0303703, FBtr0303672, FBtr0303673, FBtr0303682, FBtr0303690, FBtr0342746, FBtr0074298, FBtr0344944, FBtr0303704, FBtr0303701, FBtr0303661, FBtr0331170, FBtr0290121, FBtr0303676, FBtr0303699, FBtr0303657, FBtr0303681, FBtr0303660, FBtr0303707, FBtr0303686, FBtr0303693, FBtr0303683, FBtr0303665, FBtr0303702, FBtr0303675, FBtr0303697, FBtr0303678, FBtr0303692, FBtr0303700, FBtr0303695
Protein sequencees
EnsemblGenome_PRO: FBpp0309614, FBpp0110321, FBpp0074073, FBpp0110322, FBpp0292688, FBpp0292675, FBpp0292704, FBpp0292694, FBpp0292696, FBpp0292676, FBpp0292708, FBpp0292685, FBpp0292688, FBpp0292683, FBpp0292722, FBpp0292686, FBpp0292697, FBpp0292673, FBpp0292691, FBpp0292711, FBpp0292672, FBpp0292715, FBpp0292684, FBpp0292701, FBpp0292702, FBpp0292680, FBpp0292713, FBpp0292681, FBpp0292723, FBpp0292679, FBpp0292706, FBpp0292687, FBpp0292705, FBpp0292720, FBpp0292689, FBpp0292690, FBpp0292699, FBpp0292707, FBpp0074073, FBpp0309614, FBpp0311217, FBpp0292721, FBpp0292718, FBpp0292678, FBpp0303597, FBpp0288560, FBpp0292693, FBpp0292716, FBpp0292674, FBpp0292698, FBpp0292677, FBpp0292724, FBpp0292703, FBpp0292710, FBpp0292700, FBpp0292682, FBpp0292719, FBpp0292692, FBpp0292714, FBpp0292695, FBpp0292709, FBpp0292717, FBpp0292712
RefSeq: NP_001188622.1, NP_001036281.1, NP_001188643.1, NP_001188624.1, NP_001188604.1, NP_001188623.1, NP_001188637.1, NP_001188606.1, NP_001188650.1, NP_001138205.1, NP_001188649.1, NP_001259619.1, NP_001188640.1, NP_001188633.1, NP_001188625.1, NP_001188601.1, NP_001188621.1, NP_001188627.1, NP_001188611.1, NP_001188644.1, NP_001188613.1, NP_001188638.1, NP_001188626.1, NP_001188620.1, NP_001188639.1, NP_001188616.1, NP_001188609.1, NP_001188648.1, NP_001188646.1, NP_001188652.1, NP_001188612.1, NP_001188630.1, NP_001188617.1, NP_001188618.1, NP_001188636.1, NP_001188647.1, NP_001188610.1, NP_001188628.1, NP_001188651.1, NP_001188634.1, NP_001188631.1, NP_523371.2, NP_001188605.1, NP_001285333.1, NP_001188600.1, NP_001188632.1, NP_001285332.1, NP_001188607.1, NP_001188645.1, NP_001188603.1, NP_001188614.1, NP_001188615.1, NP_001188635.1, NP_001188602.1, NP_001188619.1, NP_001036280.1, NP_001188641.1, NP_001188642.1, NP_001188629.1, NP_001188608.1
Others
UniRef100: UniRef100_M9MSC7, UniRef100_M9MSP2, UniRef100_M9MSD9, UniRef100_M9MSD6, UniRef100_M9MS79, UniRef100_M9MSC3, UniRef100_M9MSP7, UniRef100_M9MSA3, UniRef100_M9MS71, UniRef100_M9MSP9, UniRef100_M9MSE6, UniRef100_M9MSE1, UniRef100_M9MS92, UniRef100_M9MS83, UniRef100_M9MS66, UniRef100_M9MSF1, UniRef100_M9MS65, UniRef100_M9MSB4, UniRef100_M9MSB8, UniRef100_M9MSD7, UniRef100_M9MSE0, UniRef100_M9MS69, UniRef100_M9MSP1, UniRef100_M9MSE7, UniRef100_M9MS95, UniRef100_M9MS78, UniRef100_M9MSE9, UniRef100_M9MSE3, UniRef100_M9MSA4, UniRef100_M9MS96, UniRef100_P35500, UniRef100_M9MSD2, UniRef100_M9MS87, UniRef100_M9MSE2, UniRef100_M9MS61, UniRef100_M9MSP3, UniRef100_M9MSP5, UniRef100_M9MS99, UniRef100_M9MS91, UniRef100_M9MSP8, UniRef100_X2JFE8, UniRef100_M9MSP6, UniRef100_M9MSE4, UniRef100_B7Z0Z2, UniRef100_M9MSF2, UniRef100_M9MSD5, UniRef100_M9MS88, UniRef100_M9MSP4, UniRef100_M9MSQ0, UniRef100_M9MS75, UniRef100_M9MSA0, UniRef100_M9MS84, UniRef100_M9MS73, UniRef100_M9MSD8
UniRef90: UniRef90_M9MSE3, UniRef90_P35500, UniRef90_M9MSE1, UniRef90_P35500-3, UniRef90_P35500-7, UniRef90_M9MSD9, UniRef90_M9MS99, UniRef90_M9MSP8, UniRef90_M9MSA4, UniRef90_M9MS91
UniRef50: UniRef50_M9MSP8, UniRef50_P35500, UniRef50_M9MSA4, UniRef50_M9MSD9
UniGene: Dm.22809

全选

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