| Type | Description |
|---|---|
| Definition | amyloid P component, serum |
| Date | Results | Publications |
|---|---|---|
| 2019-05-18 10:30:00 | Macrophages pretreated with SAP displayed reduced fungal phagocytosis, reduced secretion of inflammatory cytokines (IFN-gamma, IL-6, and TNF-alpha), and increased secretion of the anti-inflammatory cytokine IL-10. | 30862745 |
| 2019-02-02 10:08:00 | Antiamyloidogenic and proamyloidogenic chaperone effects of C-reactive protein and serum amyloid P component. | 28434325 |
| 2017-07-22 10:40:00 | The findings suggest that the F57I mutation affects the aggregation process of lysozyme resulting in the formation of cytotoxic species and that SAP is able to prevent cell death in the F57I flies by preventing accumulation of toxic F57I structures. | 27428539 |
| 2017-05-20 10:59:00 | Data suggest that SAP (serum amyloid P-component) interacts with at least 33 proteins/ligands in plasma containing physiological calcium levels; these ligands can be categorized to include apolipoproteins, complement system proteins, coagulation proteins, and components that regulate proteolysis. | 28098450 |
| 2017-05-06 10:21:00 | Data suggest that serum haptoglobin, fetuin-A, platelet factor-4, hs-CRP (high sensitive-C-reactive protein), SAP (serum amyloid P), AGP (alpha1-acid glycoprotein) levels of adolescents with metabolic syndrome are significantly higher than those of controls subjects. | 27754964 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-92n, PTX2, SAP |
| Gene |
UniProtKB-ID:
SAMP_HUMAN,
V9HWP0_HUMAN
UniprotKB:
P02743,
V9HWP0
UniParc:
UPI0000135533
EMBL:
CR450313,
CH471121,
BC007058,
AL445528,
BT006750,
M10944,
X04608,
BC007039,
D00097,
FJ460512
Ensembl:
ENSG00000132703
KO:
hsa:325
|
| Nucleutide sequences |
EMBL-CDS:
AAA60302.1,
CAA28275.1,
CAG29309.1,
AAH07039.1,
AAP35396.1,
AAH07058.1,
BAA00060.1,
ACS44649.1,
EAW52781.1
Gene_ORFName:
hCG_39427
Ensembl_TRS:
ENST00000255040
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000255040
RefSeq:
NP_001630.1
|
| Others |
UniRef100:
UniRef100_P02743
UniRef90:
UniRef90_P02743
UniRef50:
UniRef50_P02743
UniGene:
Hs.507080
CCDS:
CCDS1186.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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