| Type | Description |
|---|---|
| Definition | alanyl-tRNA synthetase |
| Date | Results | Publications |
|---|---|---|
| 2019-05-18 10:50:00 | all three mutations caused a pathological phenotype of neural abnormalities when expressed in zebrafish, while expression of the human wild-type messenger RNA (mRNA) did not. Our data indicate that not only functional null or hypomorphic alleles, but also hypermorphic AARS alleles can cause dominantly inherited axonal Charcot-Marie-Tooth (CMT) disease . | 30124830 |
| Type | IDs |
|---|---|
| Synonymous | im:7146712, si:ch211-223o1.6, wu:fc48h07, zgc:113920 |
| Gene |
UniProtKB-ID:
Q1LVL3_DANRE,
F1QBG7_DANRE,
Q1LVL2_DANRE
UniprotKB:
Q1LVL3,
F1QBG7,
Q1LVL2
UniParc:
UPI00015A5D94,
UPI0000547A7C,
UPI0000547A7B
EMBL:
BX649641,
BX571681
Ensembl:
ENSDARG00000069142
KO:
dre:324940
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000136544,
ENSDART00000076695,
ENSDART00000100401
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000120649,
ENSDARP00000071166,
ENSDARP00000091174
RefSeq:
NP_001037775.1,
NP_001035124.2,
XP_005159107.1
|
| Others |
UniRef100:
UniRef100_Q1LVL3,
UniRef100_F1QBG7
UniRef90:
UniRef90_F1QBG7,
UniRef90_A0A286YAH8
UniRef50:
UniRef50_A0A286YAH8,
UniRef50_F1QBG7
UniGene:
Dr.75848
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30124830 |
Hum. Mol. Genet. Marian A J Weterman , Molly Kuo , Susan B Kenter , Sara Gordillo , Dyah W Karjosukarso , Ryuichi Takase , Marieke Bronk , Stephanie Oprescu , Fred van Ruissen , Ron J W Witteveen , Henriette M E Bienfait , Martijn Breuning , Camiel Verhamme , Ya-Ming Hou , Marianne de Visser , Anthony Antonellis , Frank Baas |
2018-12-01 | - |
| 28252024 |
Evolution of complexity in the zebrafish synapse proteome. Nat Commun Ãlex Bayés , Mark O Collins , Rita Reig-Viader , Gemma Gou , David Goulding , Abril Izquierdo , Jyoti S Choudhary , Richard D Emes , Seth G N Grant |
2017-03-02 | - |
| 28934368 |
A single Danio rerio hars gene encodes both cytoplasmic and mitochondrial histidyl-tRNA synthetases. PLoS One Ashley L Waldron , Sara Helms Cahan , Christopher S Francklyn , Alicia M Ebert |
2017-01-01 | - |
| 27895053 |
Utilising polymorphisms to achieve allele-specific genome editing in zebrafish. Biol Open Samuel J Capon , Gregory J Baillie , Neil I Bower , Jason A da Silva , Scott Paterson , Benjamin M Hogan , Cas Simons , Kelly A Smith |
2016-11-28 | - |
| 25534026 |
Mol. Biol. Evol. Daniel Petit , Elin Teppa , Anne-Marie Mir , Dorothée Vicogne , Christine Thisse , Bernard Thisse , Cyril Filloux , Anne Harduin-Lepers |
2015-04-01 |
ST3GAL3,
ST3GAL4,
ST3GAL1,
LOC103060957,
ST3GAL2,
ST3GAL6,
LOC102686537,
LOC102688818,
st3gal1,
barx2,
kdm4aa,
senp7b,
adgrg7.2,
abi3bpb,
ipmka,
rnf212b,
rnf212,
slc25a28,
adgrg7.1,
ankrd2,
neurog3,
ptprfa,
tlx2,
tlx1,
ets1,
cdon,
spon2a,
spon2b,
neurog1,
ndrg3a,
ldb2a,
ldb1a,
fli1a,
nkx2.5,
nkx2.3,
klhl41b,
cfl1,
maea,
prom1a,
eif4ebp3l,
cpne1,
aars,
pif1,
rpl5a,
polr1a,
kdm4ab,
map4k5,
loxl3b,
dact2,
pcdh15a,
ptk2aa,
eif4ebp2,
hyi,
st3gal3a,
fgfrl1a,
ergic3,
prkg1a,
rad54l,
dynlrb1,
st3gal5,
nit2,
tirap,
med8,
nkx1.2la,
dpydb,
rbm39a,
got1,
cfl1l,
sf3b3,
st3gal3b,
rpl5b,
jagn1b,
st3gal2,
st3gal8,
jagn1a,
atl3,
chrac1,
st3gal4,
cog8,
ptbp2a,
morn4,
dmbx1b,
st3gal1,
st3gal1l,
ptcd3,
tmem45a,
st3gal7,
zbtb11,
cnnm2a,
st3gal1l3,
prom2,
slc24a3,
col8a1a,
hydin,
impg2a,
flrt3,
il34,
wisp1a,
atoh8
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 16412219 |
Proteomics of early zebrafish embryos. BMC Dev. Biol. Vinzenz Link , Andrej Shevchenko , Carl-Philipp Heisenberg |
2006-01-01 |
aldh9a1a.1,
atic,
ckbb,
msna,
cat,
gnb2l1,
ctps1a,
nansa,
aars,
adsl,
hspa4a,
ywhaz,
pepd,
pa2g4a,
slmapb,
zgc:56576,
mtap,
sardh,
aldh9a1b,
pdha1a,
igbp1,
psmc1b,
serpinb1,
pcca,
ppp2r1b,
prdx1,
ikbkg,
alad,
msnb,
vtg1,
ezrb,
trap1,
vtg4,
gale
|
| 16109975 |
The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res. Ian G Woods , Catherine Wilson , Brian Friedlander , Patricia Chang , Daengnoy K Reyes , Rebecca Nix , Peter D Kelly , Felicia Chu , John H Postlethwait , William S Talbot |
2005-09-01 |
fgfr4,
pik3r3b,
trpv6,
poldip2,
dnase2,
rtf1,
ube2g1b,
ppp1r14bb,
pvalb3,
znf207b,
olig1,
sufu,
msi2a,
ppp4ca,
ppp1cb,
socs9,
nhp2,
kat8,
laptm4a,
fsta,
mthfd2,
mob1a,
dyrk1aa,
greb1l,
fn1a,
aldh9a1a.1,
cpt2,
sh3gl1a,
vps18,
arrdc1a,
sv2bb,
idh1,
sb:cb37,
tle3b,
erbb4a,
ap1g2,
parp2,
hbl3,
dhx37,
pcsk7,
rmdn3,
gtf3ab,
kif3b,
npl,
sall1b,
pard6ga,
arfgef1,
gdf5,
cog1,
casr,
slc25a28,
urb1,
ndufv3,
trip11,
casq2,
mpz,
rps9,
vars,
spry4,
ube2ia,
dlg1,
sim2,
blzf1,
copb2,
sec22ba,
tnfsf10l,
ednraa,
pklr,
vcana,
ywhag1,
jag1a,
jag2b,
jag1b,
vim,
tfap2a,
prps1a,
atic,
cyp1a,
ckbb,
psap,
gbx1,
ptk2ab,
meis1b,
mkrn2,
rbp5,
crabp2a,
ccna2,
hdac1,
csnk1a1,
mak16,
actl6a,
dtl,
stil,
pole2,
slc25a5,
cct7,
cct3,
smc4,
kif11
|
| 16132083 |
Transcriptome analysis of zebrafish embryogenesis using microarrays. PLoS Genet. Sinnakaruppan Mathavan , Serene G P Lee , Alicia Mak , Lance D Miller , Karuturi Radha Krishna Murthy , Kunde R Govindarajan , Yan Tong , Yi Lian Wu , Siew Hong Lam , Henry Yang , Yijun Ruan , Vladimir Korzh , Zhiyuan Gong , Edison T Liu , Thomas Lufkin |
2005-08-01 |
cct6a,
hsf2,
xbp1,
cct7,
birc5b,
isl2b,
sox11b,
glud1a,
cdk9,
zfr,
rbb4l,
tcerg1a,
aars,
gspt1l,
arf2b,
psat1,
sfxn2,
aldoaa,
psmc1a,
yars,
casc3,
actb2,
copz1,
pknox1.1
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员