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3248 HPGD

3248

HPGD

15-hydroxyprostaglandin dehydrogenase

protein-coding

Homo sapiens

基因描述

Type Description
Definition 15-hydroxyprostaglandin dehydrogenase

研究结论

Date Results Publications
2021-04-13 10:07:00 Association between COX-2 and 15-PGDH polymorphisms and SLE susceptibility. 32100450
2021-02-27 13:51:00 Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. 33303683
2020-10-10 12:56:00 miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer. 30931980
2020-03-07 10:30:00 our results suggested that the rs2555639 of 15-PDGH was associated with colo-rectal cancer metastasis and should lead to further studies to validate the association of rs2555639 with predisposition to colorectal cancer metastasis in other groups, as well as to investigate the bio-logical functions of rs2555639 in colorectal cancer development and metastasis 31646799
2019-12-14 10:54:00 Down-regulation of HPGD by miR-146b-3p promotes cervical cancer cell proliferation, migration and anchorage-independent growth through activation of and AKT pathways. 30333561

名称对应

Type IDs
Synonymous 15-PGDH, PGDH, PGDH1, PHOAR1, SDR36C1
Gene
UniProtKB-ID: PGDH_HUMAN
UniprotKB: P15428
UniParc: UPI0001AE754F, UPI000000105B, UPI00017A7D73, UPI000013E354, UPI000006EEBF
EMBL: AK296642, X82460, AK300940, AK314624, CH471056, L76465, BC018986, AK300125, AC096751, DQ903072, U63296, AK300524, J05594
Ensembl: ENSG00000164120
KO: hsa:3248
Nucleutide sequences
EMBL-CDS: EAX04734.1, EAX04735.1, BAG37190.1, BAG61916.1, AAA89174.1, BAH12408.1, EAX04737.1, CAA57843.1, AAA89175.1, BAG62569.1, ABI75347.1, EAX04736.1, AAB53034.1, BAG62236.1, AAH18986.1
Ensembl_TRS: ENST00000542498, ENST00000422112, ENST00000541923, ENST00000510901, ENST00000296522, ENST00000296521
Protein sequencees
Ensembl_PRO: ENSP00000296521, ENSP00000398720, ENSP00000422418, ENSP00000443644, ENSP00000296522, ENSP00000438017
RefSeq: NP_001243234.1, NP_001243230.1, NP_001139288.1, NP_001243236.1, NP_001350503.1, NP_001243235.1, NP_000851.2
Others
UniRef100: UniRef100_P15428
UniRef90: UniRef90_P15428
UniRef50: UniRef50_P15428
UniGene: Hs.596913
CCDS: CCDS58934.1, CCDS3821.1, CCDS54821.1, CCDS58935.1, CCDS58933.1

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