| Type | Description |
|---|---|
| Definition | highwire |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 10:41:00 | Highwire downregulates dNmnat to promote evoked synaptic release, suggesting that Highwire balances the axoprotective and synapse-inhibitory functions of dNmnat. | 30692130 |
| 2019-01-19 10:04:00 | Study provide specific evidence that in Drosophila melanogaster hiw plays an important role in the regulation of behavioral nociception and nociceptor sensitivity through the bone morphogenetic protein (BMP) pathway. | 30001326 |
| 2018-07-14 11:04:00 | Results indicate that the ability of faf, hiw or Rdl to modulate sleep and protect against cognitive impairments during waking is circuit dependent. Decreasing hiw and Rdl within the Mushroom Bodies protects against the negative effects of sleep deprivation as indicated by the absence of a subsequent homeostatic response, or deficits in short-term memory. | 29109678 |
| 2017-05-06 10:08:00 | Highwire promotes axon termination, pruning and synaptogenesis. | 28100586 |
| 2014-01-11 11:15:00 | The dual leucine zipper kinase (DLK) signaling pathway in Drosophila, which consists of Highwire and Wallenda and controls axonal growth, regeneration, and degeneration, is also involved in dendritic growth in vivo. | 23750116 |
| Type | IDs |
|---|---|
| Synonymous | CG32592, CG9041, CG9049, Dmel\CG32592, Hiw |
| Gene |
UniProtKB-ID:
HIW_DROME,
X2JF19_DROME
UniprotKB:
Q9NB71,
X2JF19
UniParc:
UPI00001E2D37
EMBL:
AY113376,
AF262977,
AE014298
EnsemblGenome:
FBgn0030600
KO:
dme:Dmel_CG32592
|
| Nucleutide sequences |
EMBL-CDS:
AAM29381.1,
AAF76150.1,
AAF48411.2,
AHN59728.1
Gene_ORFName:
CG32592,
Dmel_CG32592,
CG32592
EnsemblGenome_TRS:
FBtr0346087,
FBtr0073970,
FBtr0073970,
FBtr0346087
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0311921,
FBpp0073787,
FBpp0311921,
FBpp0073787
RefSeq:
NP_511159.3,
NP_001285258.1
|
| Others |
UniRef100:
UniRef100_Q9NB71
UniRef90:
UniRef90_Q9NB71
UniRef50:
UniRef50_Q9NB71
UniGene:
Dm.3259
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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