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32398 NetA

32398

NetA

Netrin-A

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Netrin-A

研究结论

Date Results Publications
2019-07-06 13:15:00 Here we show that M3-specific innervation by both neurons is coordinated by Drosophila Fezf (dFezf), a conserved transcription factor that is selectively expressed by the earlier targeting input neuron. In this cell, dFezf instructs layer specificity and activates the expression of a secreted molecule (Netrin) that regulates the layer specificity of the other input neuron. 29513217
2016-08-06 10:33:00 mutation of mushroom body defect (mud) dramatically enhances the phenotype of Netrin or frazzled mutants, resulting in many more axons failing to cross the midline, although mutations in mud alone have little effect. 26893348
2015-07-25 11:30:00 Contact-mediated cell adhesion via Fmi acts in addition to the Net/Fra guidance system during axon pathfinding across the midline, underlining the importance of PCP molecules during vertebrates and invertebrates midline development. 25440577
2015-01-24 13:11:00 adult Drosophila lacking both netrin genes, NetA and NetB, have fertility defects in both sexes together with an inability to fly and reduced viability. 23977313
2014-07-19 13:02:00 In peripodial cells Frazzled is endocytosed and undergoes NetA-dependent degradation, which is required for eversion. 24225841

名称对应

Type IDs
Synonymous CG18657, CT27014, Dmel\CG18657, NetrinA, net, netA, netrin, netrin A
Gene
UniProtKB-ID: NETA_DROME, M9NF48_DROME, X2JEZ9_DROME
UniprotKB: Q24567, M9NF48, X2JEZ9
UniParc: UPI0000076C31, UPI000034DE50
EMBL: U63736, AE014298, U60316, AY089580
EnsemblGenome: FBgn0015773
KO: dme:Dmel_CG18657
Nucleutide sequences
EMBL-CDS: AAB17533.1, AAF48380.3, AAB17547.1, AAL90318.1, AFH07381.1, AHN59713.1
Gene_ORFName: CG18657, Dmel_CG18657, CG18657, CG18657, Dmel_CG18657
EnsemblGenome_TRS: FBtr0073942, FBtr0346088, FBtr0308337, FBtr0346088, FBtr0073942
Protein sequencees
EnsemblGenome_PRO: FBpp0073759, FBpp0311922, FBpp0300656, FBpp0311922, FBpp0073759
RefSeq: NP_001285243.1, NP_001245667.1, NP_511154.3
Others
UniRef100: UniRef100_M9NF48, UniRef100_Q24567
UniRef90: UniRef90_Q24567, UniRef90_M9NF48
UniRef50: UniRef50_Q24567
UniGene: Dm.2915

全选

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