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323 APBB2

323

APBB2

amyloid beta precursor protein binding family B member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition amyloid beta precursor protein binding family B member 2

研究结论

Date Results Publications
2019-11-23 10:57:00 In this genome-wide association study, variants at the APBB2 locus demonstrated differential association with primary open-angle glaucoma by ancestry. 31688885
2019-01-05 11:32:00 Genetic variants in the APBB2 gene were associated with use of amphetamine in opioid dependent patients under methadone maintenance treatment. The haplotype combinations further confirmed this observation, especially in the patients with a positive urine morphine test result. The major genotype and allele type carriers showed a two-time higher risk of amphetamine use than the minor allele type carriers. 29330135
2016-07-16 10:41:00 APBB2 was differentially expressed between Fibromyalgia patients and healthy controls. 27157394
2016-05-28 11:32:00 results provide additional evidence of a genetic interaction between GSK3beta and APBB2 and further suggest that GSK3beta is involved in the pathophysiology of both of the primary neuropathologies of Alzheimer's disease 26194614
2013-09-07 10:40:00 The APBB2 rs13133980 G allele was over-represented in centenarians with severe cognitive impairment compared to individuals without this disability. 23384821

名称对应

Type IDs
Synonymous FE65L, FE65L1
Gene
UniProtKB-ID: APBB2_HUMAN, B4E2F2_HUMAN, Q5I0G1_HUMAN, G5E9Y1_HUMAN, B4DJ88_HUMAN
UniprotKB: Q92870, B4E2F2, Q5I0G1, G5E9Y1, B4DJ88
UniParc: UPI00004A0DA9, UPI000059675C, UPI0001B8E1D4, UPI00017A716F, UPI00017A87B9, UPI00003CE423, UPI000020BBFD, UPI000020BBF7
EMBL: AC096712, CH471069, U62325, BC027946, AC108937, AC131953, AK226179, AC093804, AK304247, AK299800, AK295974, BC088372
Ensembl: ENSG00000163697
KO: hsa:323
Nucleutide sequences
EMBL-CDS: AAH27946.2, BAG61676.1, AAC50805.1, BAG65114.1, AAH88372.1, EAW92977.1, BAG58750.1
Gene_ORFName: hCG_33089
Ensembl_TRS: ENST00000543538, ENST00000508593, ENST00000502841, ENST00000513140, ENST00000295974, ENST00000504305, ENST00000506352
Protein sequencees
Ensembl_PRO: ENSP00000426018, ENSP00000427211, ENSP00000425802, ENSP00000439357, ENSP00000295974, ENSP00000423765, ENSP00000421539
RefSeq: XP_006714073.1, XP_016863638.1, XP_016863640.1, XP_006714072.1, XP_016863645.1, XP_016863647.1, NP_001317587.1, XP_016863632.1, NP_001159522.1, NP_001159523.1, NP_001159524.1, NP_775098.2, XP_016863634.1, XP_011511989.1, NP_001317585.1, XP_016863633.1, XP_016863637.1, NP_001159525.1, XP_006714070.1, XP_006714074.1, NP_004298.1, XP_006714068.1, NP_001159526.1, XP_016863641.1, XP_016863635.1, XP_011511990.1, XP_016863643.1, XP_011511988.1, XP_006714075.1, XP_016863636.1, XP_016863646.1, XP_006714071.1
Others
UniRef100: UniRef100_B4DJ88, UniRef100_Q92870, UniRef100_B4E2F2, UniRef100_G5E9Y1, UniRef100_A0A2I3TIR0
UniRef90: UniRef90_Q92870, UniRef90_Q92870-2
UniRef50: UniRef50_Q92870
UniGene: Hs.479602
CCDS: CCDS54762.1, CCDS54761.1, CCDS43224.1, CCDS54760.1

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