| Type | Description |
|---|---|
| Definition | homeobox C13 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 12:58:00 | The homeobox transcription factor HOXC13 upregulates human papillomavirus E1 gene expression and contributes to viral genome maintenance. | 31642514 |
| 2020-05-16 12:31:00 | that HOXC13-AS exerted oncogenic function in nasopharyngeal carcinoma via regulating miR-383-3p/HMGA2 axis | 30536950 |
| 2019-09-14 10:53:00 | The results have identified a homozygous 28 base-pair insertion mutation in exon 2 of the HOXC13 gene in both sisters in an Iranian family. This mutation was also present in both parents in the heterozygous state. | 29278420 |
| 2018-08-25 11:34:00 | we report a novel nonsense variant (c.265C>T, p.Gln89*) in the HOXC13 gene, which resulted in a premature termination codon and is predicted either to produce a truncated protein without an essential DNA binding homeodomain or more likely to undergo nonsense-mediated RNA decay- ultimately producing the PHNED (pure hair and nail ectodermal dysplasia) phenotype. | 28543635 |
| 2018-02-10 10:28:00 | Study showed that HOXC13 expression was significantly elevated in esophageal squamous cell carcinoma (ESCC), and correlated with worse clinical characteristics and poorer prognosis. HOXC13 promoted proliferation and inhibited apoptosis through repressing transcription of CASP3. | 29168599 |
| Type | IDs |
|---|---|
| Synonymous | ECTD9, HOX3, HOX3G |
| Gene |
UniProtKB-ID:
HXC13_HUMAN
UniprotKB:
P31276
UniParc:
UPI000012CF7F
EMBL:
BC090850,
AF263466,
AK024027,
BT009908,
AF255676
Ensembl:
ENSG00000123364
KO:
hsa:3229
|
| Nucleutide sequences |
EMBL-CDS:
AAP88910.1,
AAF67760.1,
AAH90850.1,
BAB14786.1,
AAF73439.1
Ensembl_TRS:
ENST00000243056
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000243056
RefSeq:
NP_059106.2
|
| Others |
UniRef100:
UniRef100_P31276
UniRef90:
UniRef90_P50207
UniRef50:
UniRef50_P50207
UniGene:
Hs.118608
CCDS:
CCDS8865.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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