| Type | Description |
|---|---|
| Definition | homeobox B8 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:14:00 | Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1. | 31591481 |
| 2020-06-27 11:28:00 | miR-32-5p significantly downregulated in cervical cancer (CCa) tissues and cells. Bioinformatics and Luciferase method screened HOXB8 as a downstream regulatory target of miR-32-5p. Besides, HOXB8 was incredibly highly expressed in CCa tissues and cells. Decreased expression of HOXB8 resulting from upregulation of miR-32-5p could weaken cell proliferation, clone formation, invasion and migration ability of HeLa cells. | 30657550 |
| 2020-04-11 10:11:00 | Knockdown of HOXB8 abolished the effects of miR-128 inhibitor on ovarian cancer cell proliferation and paclitaxel sensitivity. Summarily, miR-128 displayed a tumour suppressor role in ovarian cancer via targeting HOXB8. | 31271703 |
| 2020-01-11 10:44:00 | our results indicated that microRNA-27a-3p acts as a tumor suppressor in non-small lung cancer via targeting homeobox B8. | 31319766 |
| 2019-12-21 10:53:00 | knockdown of HOXB8 could suppress tumorigenesis and metastasis in OS through regulation of the Wnt/beta-catenin signaling pathway | 30954562 |
| Type | IDs |
|---|---|
| Synonymous | HOX2, HOX2D, Hox-2.4 |
| Gene |
UniProtKB-ID:
HXB8_HUMAN,
Q8N8T3_HUMAN,
I3L3R1_HUMAN
UniprotKB:
P17481,
Q8N8T3,
I3L3R1
UniParc:
UPI000007012D,
UPI000012CF63,
UPI0000EE637C
EMBL:
X16173,
AY014293,
AY014294,
AK096222,
AC103702,
CH471109
Ensembl:
ENSG00000120068
KO:
hsa:3218
|
| Nucleutide sequences |
EMBL-CDS:
CAA34295.1,
AAG42143.1,
BAC04730.1,
EAW94723.1
Gene_ORFName:
hCG_1639847
Ensembl_TRS:
ENST00000239144,
ENST00000576562
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000239144,
ENSP00000460659
RefSeq:
XP_005257343.1,
NP_076921.1,
XP_016880053.1
|
| Others |
UniRef100:
UniRef100_I3L3R1,
UniRef100_Q8N8T3,
UniRef100_P17481
UniRef90:
UniRef90_Q8N8T3,
UniRef90_P17481
UniRef50:
UniRef50_P31273
UniGene:
Hs.514292
CCDS:
CCDS11533.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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