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32158 cac

32158

cac

cacophony

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition cacophony

研究结论

Date Results Publications
2020-03-28 11:26:00 Deletion of exon 7 caused a decrease in cacophony protein expression but not total transcript levels, caused reduced locomotory activity in adults, and locomotion defects in third instar larvae. 30397173
2020-03-21 10:49:00 Study finds that the abundance of endogenous Cac is modulated during presynaptic homeostatic potentiation, but does not change during presynaptic homeostatic depression. 30692227
2018-05-19 11:46:00 Strikingly the absence of any of DLG proteins at the presynaptic terminal disrupts the clustering and localization of the calcium channel DmCa1A subunit (Cacophony), decreases the action potential-evoked release probability and alters short-term plasticity. 27573697
2017-10-14 13:05:00 Motor defects in TDP-43 mutants can be rescued by expression of cacophony in motor neurons and by expression in two pairs of neurons in the brain. 28847811
2017-08-26 11:09:00 the novel R1673P allele of CACNA1A produces neurodegenerative phenotypes in flies and human, likely due to a toxic gain of function 28742085

名称对应

Type IDs
Synonymous 13, CAC, CG1522, CG15928, CG43368, Ca-alpha1A, Ca[[V]]2.1, Cac, Cac1, DMCA1A, Dmca1A, Dmcalpha1A, Dmel\CG43368, Dmel_CG1522, Dmel_CG15928, EE171, H18, H47, L13, P18, alpha1A, cac1, dCac1, l(1)11Aa, l(1)13, l(1)L13, ldg, nbA, nonB, opm18, opm47
Gene
UniProtKB-ID: CAC1A_DROME, M9NF25_DROME, Q59E53_DROME, M9NDV1_DROME, M9NGZ9_DROME, Q59E51_DROME, M9NEE2_DROME, M9PHD4_DROME, Q59E50_DROME, Q59E52_DROME
UniprotKB: P91645, M9NF25, Q59E53, M9NDV1, M9NGZ9, Q59E51, M9NEE2, M9PHD4, Q59E50, Q59E52
UniParc: UPI000150636B, UPI000034DE38, UPI00004ED462, UPI00004ED461, UPI000237F793, UPI00004ED463, UPI00004C2D1C, UPI00004C2D1B, UPI000237F798, UPI000034DE3A, UPI00000072A3, UPI000034DE39, UPI00004ED464, UPI000293F47E
EMBL: U88664, U88665, AE014298, U55776
EnsemblGenome: FBgn0263111
KO: dme:Dmel_CG43368
Nucleutide sequences
EMBL-CDS: AAS65323.1, AAF48120.2, AAS65326.1, AAS65324.1, AAB53271.1, AAS65325.1, AAC47406.1, AAB53272.1, AAS65322.1, AFH07351.1, AAX52486.1, AFH07353.1, AFH07352.1, AAX52488.1, AFH07350.1, AGB95320.1, AAX52489.1, AAX52487.1
Gene_ORFName: CG43368, Dmel_CG43368, CG43368, CG43368, Dmel_CG43368, CG43368, Dmel_CG43368, Dmel_CG43368, CG43368, Dmel_CG43368, CG43368, CG43368, Dmel_CG43368, Dmel_CG43368, CG43368, Dmel_CG43368, CG43368, CG43368, Dmel_CG43368
EnsemblGenome_TRS: FBtr0307318, FBtr0307322, FBtr0307319, FBtr0307320, FBtr0308609, FBtr0307324, FBtr0307314, FBtr0308609, FBtr0307322, FBtr0307325, FBtr0307313, FBtr0307323, FBtr0332391, FBtr0307316, FBtr0307315
Protein sequencees
EnsemblGenome_PRO: FBpp0298320, FBpp0298321, FBpp0300833, FBpp0298323, FBpp0298319, FBpp0298325, FBpp0298315, FBpp0298323, FBpp0300833, FBpp0298326, FBpp0298314, FBpp0298324, FBpp0304665, FBpp0298317, FBpp0298316
RefSeq: NP_996420.1, NP_001014735.1, NP_996416.1, NP_001259477.1, NP_001014734.1, NP_511133.2, NP_001014733.1, NP_001245637.1, NP_001014732.1, NP_001356943.1, NP_996417.1, NP_996418.1, NP_001356945.1, NP_001356944.1, NP_001245638.1, NP_001245636.1, NP_001245639.1, NP_996419.1
Others
UniRef100: UniRef100_P91645, UniRef100_M9NEE2, UniRef100_Q59E51, UniRef100_M9NF25, UniRef100_M9NGZ9, UniRef100_Q59E52, UniRef100_Q59E50, UniRef100_M9PHD4, UniRef100_Q59E53
UniRef90: UniRef90_P91645
UniRef50: UniRef50_P91645
UniGene: Dm.2395

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