| Type | Description |
|---|---|
| Definition | homeobox B5 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-30 13:02:00 | HOXB5 promotes malignant progression in pancreatic cancer via the miR-6732 pathway. | 31876226 |
| 2020-12-19 13:46:00 | HOXB5 acts as an oncogenic driver in head and neck squamous cell carcinoma via EGFR/Akt/Wnt/beta-catenin signaling axis. | 31864826 |
| 2019-11-30 10:54:00 | miR625 upregulation directly targeted HOXB5 to deactivate the Wnt/betacatenin signaling pathway in nonsmall cell lung cancer cells in vitro and in vivo. | 31115501 |
| 2019-01-19 11:45:00 | In breast cancer cells, HOXB5 regulates EGFR expression at the transcriptional level by directly binding to its promoter region and promotes phosphorylation of EGFR as well as its downstream effectors | 30115380 |
| 2018-08-18 11:21:00 | for the first time we have shown that knockdown of HOXB5 significantly inhibited non-small cell lung cancer cell proliferation, invasion, metastasis, and epithelial-mesenchymal transformation, partly through the Wnt/beta-catenin signaling pathway | 28337958 |
| Type | IDs |
|---|---|
| Synonymous | HHO.C10, HOX2, HOX2A, HU-1, Hox2.1 |
| Gene |
UniProtKB-ID:
HXB5_HUMAN
UniprotKB:
P09067
UniParc:
UPI000012CF58
EMBL:
M86726,
BC117247,
M92299,
AK314964,
K02572,
X03794,
AF287967
Ensembl:
ENSG00000120075
KO:
hsa:3215
|
| Nucleutide sequences |
EMBL-CDS:
AAG31553.1,
AAI17248.1,
AAA52682.1,
AAA52681.1,
BAG37466.1,
CAA27420.1,
AAB59430.1
Ensembl_TRS:
ENST00000239151
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000239151
RefSeq:
NP_002138.1
|
| Others |
UniRef100:
UniRef100_P09067
UniRef90:
UniRef90_P09067
UniRef50:
UniRef50_P09067
UniGene:
Hs.654456
CCDS:
CCDS11530.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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