| Type | Description |
|---|---|
| Definition | homeobox B1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 13:45:00 | The results from this study demonstrate the potential of hsa-let-7g/HOXB1 axis as a therapeutic target for the treatment of lung cancer. | 32102121 |
| 2019-07-20 13:26:00 | a homozygous c.74_82dup (p.Pro28delinsHisSerAlaPro) variant was identified in one individual with double outlet right ventricle (DORV). We also identified five previously reported polymorphisms (rs35114525, rs12946855, rs14534040, rs12939811, and rs7207109) in 18 patients (12 DORV and 6 perimembranous VSD). Our study did not show any pathogenic alterations in the coding region of HOXB1 among patients with VSD. | 29923154 |
| 2017-10-28 11:59:00 | This is the first disease-associated HOXB1 mutation with a likely loss-of-function effect suggesting that all HOXB1 variants reported so far also have severe impact on activity of this transcriptional regulator | 27144914 |
| 2017-02-18 10:49:00 | findings revealed a novel homozygous mutation p.Arg230Trp (c.688C>T) within the HOXB1 gene of three members of a Turkish family with hereditary congenital facial paresis (HCFP3) | 27640920 |
| 2016-07-16 10:35:00 | HOXB1 functions as a tumor suppressor, regulated by miR-3175 in glioma. | 26565624 |
| Type | IDs |
|---|---|
| Synonymous | HCFP3, HOX2, HOX2I, Hox-2.9 |
| Gene |
UniProtKB-ID:
HXB1_HUMAN
UniprotKB:
P14653
UniParc:
UPI0000163BFF,
UPI000050ED48
EMBL:
BC096191,
X16666,
AC103702,
BC099633
Ensembl:
ENSG00000120094
KO:
hsa:3211
|
| Nucleutide sequences |
EMBL-CDS:
AAH96191.1,
AAH99633.1,
CAA34656.1
Ensembl_TRS:
ENST00000577092,
ENST00000239174
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355140,
ENSP00000459066
RefSeq:
NP_002135.2
|
| Others |
UniRef100:
UniRef100_P14653
UniRef90:
UniRef90_P14653
UniRef50:
UniRef50_P14653
UniGene:
Hs.99992
CCDS:
CCDS32675.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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