| Type | Description |
|---|---|
| Definition | chromodomain helicase DNA binding protein 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:21:00 | CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression. | 33060836 |
| 2021-01-16 15:56:00 | CHD7 regulates cardiovascular development through ATP-dependent and -independent activities. | 33127760 |
| 2020-11-21 13:22:00 | CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. | 32883883 |
| 2019-12-07 10:49:00 | Study using human SH-SY5Y neuroblastoma and 293T cells and transgenic mouse model show that CHD7 directly regulates expression of retinoic acid synthetic enzyme ALDH1A3. Results indicate that ALDH1A3 acts with CHD7 in a common genetic pathway to regulate inner ear development, providing insights for exploration of the pathogenic mechanisms underlying CHARGE syndrome. | 29467333 |
| 2018-12-22 11:12:00 | Data show that chromodomain helicase DNA-binding protein 7 (Chd7) is required for the maintenance of open chromatin and thus activation of genes essential for granule neuron differentiation. | 28317875 |
| Type | IDs |
|---|---|
| Synonymous | A730019I05Rik, Cycn, Cyn, Dz, Edy, Flo, GENA 47, GENA 60, Gena 52, Lda, Mt, Obt, Todo, WBE1, Whi, metis |
| Gene |
UniProtKB-ID:
CHD7_MOUSE
UniprotKB:
A2AJK6
UniParc:
UPI00006048E6,
UPI000059DED7,
UPI000152633E
EMBL:
AK042727,
BC034239,
AK171051,
AL732627,
AK172025,
AL805903,
AK171857
Ensembl:
ENSMUSG00000041235
KO:
mmu:320790
|
| Nucleutide sequences |
EMBL-CDS:
AAH34239.2,
BAC31343.1,
BAE42783.1,
BAE42213.1,
BAE42701.1
Ensembl_TRS:
ENSMUST00000039267,
ENSMUST00000051558
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043903,
ENSMUSP00000059079
RefSeq:
XP_006538069.1,
NP_001342311.1,
NP_001264078.1,
XP_006538068.1,
XP_006538067.1
|
| Others |
UniRef100:
UniRef100_A2AJK6
UniRef90:
UniRef90_Q9P2D1
UniRef50:
UniRef50_Q9P2D1
UniGene:
Mm.138792
CCDS:
CCDS38689.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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