| Type | Description |
|---|---|
| Definition | cancer susceptibility candidate 1 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | Las1 is part of the complex multigenic Pas1 locus, with a functional role for its intragenic polymorphisms and AA changes in lung tumor susceptibility. It may be a tumor suppressor. | 15064703 |
| 2010-01-21 00:00:00 | The differential degradation of Las1-A/J and Las-B6 produced from the 2 corresponding alleles, has important implications for its intracellular function and may eventually explain Las1-A/J in lung tumorigenesis. | 17974961 |
| 2006-09-29 08:39:00 | Casc1 knockout mouse tumor bioassays showed that Casc1-deficient mice were susceptible to chemical induction of lung tumors. | 16862160 |
| 2006-09-29 08:39:00 | Whole-genome association analyis of lung tumor susceptibility refined the Pas1 locus to a region of less than 0.5 Mb containing two strong candidates, Kras2 and Casc1 (also known as Las1). | 16862160 |
| Type | IDs |
|---|---|
| Synonymous | A230084G12Rik, Las1 |
| Gene |
UniProtKB-ID:
CASC1_MOUSE,
A0A0R4J0S9_MOUSE
UniprotKB:
Q6TDU8,
A0A0R4J0S9
UniParc:
UPI000043A730,
UPI00001D86A6,
UPI00000EA3E8,
UPI0001722182
EMBL:
AC121950,
AY490384,
AK132912,
AK034148,
AY485607,
AY423542,
AC157091,
BC120743,
AY485608,
AY490383,
BC125423
Ensembl:
ENSMUSG00000043541
KO:
mmu:320662
|
| Nucleutide sequences |
EMBL-CDS:
AAQ93498.1,
AAI25424.1,
BAC28607.1,
AAS55697.1,
BAE21417.1,
AAI20744.1,
AAT72330.1,
AAS55696.1,
AAT72331.1
Ensembl_TRS:
ENSMUST00000060797
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000062279
RefSeq:
XP_036022124.1,
XP_006507033.1,
XP_011239893.1,
XP_006507037.1,
XP_011239892.1,
XP_006507035.1,
XP_017177134.1,
XP_006507036.1,
XP_011239895.1,
XP_017177135.1,
XP_030111323.1,
XP_011239891.1,
XP_006507041.1,
XP_011239890.1,
XP_011239894.1,
XP_011239896.1,
XP_006507034.1,
NP_796196.3
|
| Others |
UniRef100:
UniRef100_Q6TDU8,
UniRef100_A0A0R4J0S9
UniRef90:
UniRef90_Q6TDU8
UniRef50:
UniRef50_Q6TDU8
UniGene:
Mm.207779
CCDS:
CCDS39705.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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