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32049 Klp10A

32049

Klp10A

Kinesin-like protein at 10A

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Kinesin-like protein at 10A

研究结论

Date Results Publications
2020-07-25 10:27:00 Dissociation of Piwi from nuage occurs at the depolymerizing microtubules of the central spindle, mediated by a microtubule-depolymerizing kinesin, Klp10A. Depletion of klp10A delays the return of Piwi to the nucleus and affects piRNA production, suggesting the role of nuclear-cytoplasmic communication in piRNA biogenesis. 32168327
2018-12-22 12:06:00 Near atomic resolution cryo-electron microscopy structures of Drosophila melanogaster kinesin-13 KLP10A protein constructs in complex with curved tubulin protofilaments or bound to the microtubule lattice show how the kinesin-13-specific loop-2 couple ATP-hydrolysis conformational changes in the motor domain with tubulin bending and microtubule depolymerization. 29695795
2017-10-07 11:08:00 The authors propose that klp10A functions to counteract undesirable asymmetries that may result as a by-product of achieving asymmetries essential for successful stem cell divisions. 27885983
2017-07-01 11:57:00 In the absence of Klp10A the distribution of Drosophila pericentrin-like protein (Dplp), Sas-4 and Sak/Plk4 that are restricted in control testes to the proximal end of the centriole increase along the centriole length. 27764551
2016-12-24 10:34:00 Interaction Modes of the Kinesin-13 Motor Domain with the Microtubule 27074684

名称对应

Type IDs
Synonymous CG1453, DmCG1453, DmKLP10A, DmKlp10A, Dmel\CG1453, KIF 2A, KIF2A/B/C, KLP10A, KLP10a, Kif2A, anon-WO03040301.142, klp10A
Gene
UniProtKB-ID: KI10A_DROME, A4V4A1_DROME
UniprotKB: Q960Z0, A4V4A1
UniParc: UPI0000083BB1
EMBL: AE014298, AY051763
EnsemblGenome: FBgn0030268
KO: dme:Dmel_CG1453
Nucleutide sequences
EMBL-CDS: AAK93187.1, AAN09282.1, AHN59579.1, AAN09285.1, AAN09283.1, AAF48003.2, AAN09284.1
Gene_ORFName: CG1453, Dmel_CG1453, CG1453
EnsemblGenome_TRS: FBtr0346270, FBtr0073479, FBtr0073477, FBtr0073478, FBtr0073476, FBtr0073475, FBtr0073478, FBtr0346270, FBtr0073475, FBtr0073479, FBtr0073477, FBtr0073476
Protein sequencees
EnsemblGenome_PRO: FBpp0312027, FBpp0073332, FBpp0073335, FBpp0073331, FBpp0073334, FBpp0073333, FBpp0312027, FBpp0073334, FBpp0073335, FBpp0073332, FBpp0073333, FBpp0073331
RefSeq: NP_727491.1, NP_001285109.1, NP_727493.1, NP_727494.1, NP_572687.1, NP_727492.1
Others
UniRef100: UniRef100_Q960Z0
UniRef90: UniRef90_Q960Z0
UniRef50: UniRef50_Q960Z0
UniGene: Dm.130

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