| Type | Description |
|---|---|
| Definition | Ca2+-dependent activator protein for secretion 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 12:16:00 | The data suggest that CADPS2-mediated secretion of BDNF/NT-3 may be involved in development and maturation of synapses and in the balance between inhibitory and excitatory synapses. | 30594389 |
| 2019-04-13 10:20:00 | Study looked at synaptic microstructures of hippocampal mossy fiber (MF) terminals in Calcium-dependent activator protein for secretion 2 (Cadps2) knockout mice. Findings suggest that CADPS2 plays a critical role in MF synaptic development and functional organization. | 29689341 |
| 2018-01-19 18:00:00 | results suggest that deregulated gene expression caused by loss of Cadps2 may cause developmental deficits and/or pathological symptoms, resulting in autistic-like phenotypes | 28041965 |
| 2015-01-31 10:36:00 | CAPS2 plays an important role in subcellular locality (axonal vs. somato-dendritic) of enhanced BDNF and NT-3 release, which is indispensable for proper development of postnatal cerebellum. | 24923991 |
| 2013-03-02 10:52:00 | Data suggest that adequate levels of CAPS2 are critical for normal brain development and normal behavior; allelic changes due to copy number variation may contribute to autistic behavior. | 23159942 |
| Type | IDs |
|---|---|
| Synonymous | A230044C21Rik, Caps-2, Caps2, Cpd2 |
| Gene |
UniProtKB-ID:
CAPS2_MOUSE,
A4PI81_MOUSE,
A4PI82_MOUSE,
A4PI80_MOUSE,
A4PI83_MOUSE,
A4PI84_MOUSE
UniprotKB:
Q8BYR5,
A4PI81,
A4PI82,
A4PI80,
A4PI83,
A4PI84
UniParc:
UPI00000EA5E0,
UPI00006688AB,
UPI0000668809,
UPI0001334D30,
UPI00006688A9,
UPI00006688AA,
UPI0001334D2F,
UPI0001334D2D,
UPI0001334D2E,
UPI00002282CE,
UPI000024FA2D
EMBL:
BC080854,
BC047394,
AK046596,
BC055462,
BC059274,
AB291949,
AK038568,
AY072800,
AB291948,
AB098623,
AB291947,
AB291950,
AB291946,
AK042634,
AF000969
Ensembl:
ENSMUSG00000017978
KO:
mmu:320405
|
| Nucleutide sequences |
EMBL-CDS:
BAC32801.1,
AAH59274.1,
BAC30047.1,
BAC31314.1,
AAH55462.1,
AAL67937.1,
BAD05017.1,
AAH47394.1,
AAB58720.2,
AAH80854.1,
BAF56578.1,
BAF56579.1,
BAF56577.1,
BAF56580.1,
BAF56581.1
Ensembl_TRS:
ENSMUST00000115358,
ENSMUST00000115361,
ENSMUST00000115356,
ENSMUST00000018122
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000111015,
ENSMUSP00000111013,
ENSMUSP00000111018,
ENSMUSP00000018122
RefSeq:
XP_006505173.1,
XP_017177129.1,
NP_001239036.1,
XP_006505176.1,
XP_006505172.1,
NP_001239037.1,
XP_006505170.1,
XP_030111317.1,
NP_001239038.1,
XP_006505174.1,
NP_001239035.1,
XP_017177130.1,
NP_694803.3,
XP_036022120.1,
XP_030111318.1,
XP_006505175.1,
XP_006505178.1,
XP_006505177.1,
NP_001239034.1,
XP_006505171.1,
XP_036022121.1,
NP_001239039.1,
XP_036022119.1
|
| Others |
UniRef100:
UniRef100_A4PI81,
UniRef100_Q8BYR5,
UniRef100_A4PI80,
UniRef100_A4PI83,
UniRef100_A4PI82,
UniRef100_A4PI84
UniRef90:
UniRef90_A4PI83,
UniRef90_Q8BYR5,
UniRef90_A4PI84,
UniRef90_A4PI82,
UniRef90_A4PI81,
UniRef90_A4PI80
UniRef50:
UniRef50_Q8BYR5-6,
UniRef50_A4PI80,
UniRef50_A4PI84,
UniRef50_Q86UW7,
UniRef50_Q8BYR5
UniGene:
Mm.259632
CCDS:
CCDS57413.1,
CCDS39439.1,
CCDS57411.1,
CCDS57412.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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