| Type | Description |
|---|---|
| Definition | inositol 1,4,5-trisphosphate 3-kinase B |
| Date | Results | Publications |
|---|---|---|
| 2016-10-29 10:19:00 | Thus, non-canonical phosphoinositide 3-kinase-antagonism by Itpkb restricts pre-T cell receptor induced metabolic activation to enforce coincidence-detection of pre-T cell receptor expression and Notch-engagement. | 26880557 |
| 2016-04-09 10:38:00 | These data identify Itpkb as an essential mediator of T cell activation and suggest Itpkb inhibition as a novel approach to treat autoimmune disease. | 26121493 |
| 2015-08-08 10:04:00 | Itpkb controls hematopoietic stem cell homeostasis and prevent death from severe anemia in mice. | 25788703 |
| 2013-08-10 10:04:00 | Itpkb controls survival, proliferation and cytokine production in mouse peripheral T cells. | 22981169 |
| 2011-07-23 10:08:00 | controls survival and prevents anergy in B cells | 20452702 |
| Type | IDs |
|---|---|
| Synonymous | 1110033J02Rik, E130307H12Rik |
| Gene |
UniProtKB-ID:
B2RXC2_MOUSE
UniprotKB:
B2RXC2
UniParc:
UPI00001E2F0B
EMBL:
BC157986,
BC151160,
BC158000,
AC121838
Ensembl:
ENSMUSG00000038855
KO:
mmu:320404
|
| Nucleutide sequences |
EMBL-CDS:
AAI57987.1,
AAI58001.1,
AAI51161.1
Ensembl_TRS:
ENSMUST00000070181
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000069851
RefSeq:
NP_001074644.1,
XP_030110829.1,
XP_006496965.1,
XP_036021593.1,
XP_030110830.1
|
| Others |
UniRef100:
UniRef100_B2RXC2
UniRef90:
UniRef90_B2RXC2
UniRef50:
UniRef50_P27987
UniGene:
Mm.132535,
Mm.383297
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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