| Type | Description |
|---|---|
| Definition | homeobox A6 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:23:00 | MiR-1294 acts as a tumor suppressor in clear cell renal cell carcinoma through targeting HOXA6. | 31114997 |
| 2019-08-31 12:06:00 | Study revealed that the mRNA and protein expression levels of HOXA6 were suppressed in clear cell renal cell carcinoma (ccRCC) tissues. Its overexpression suppresses cell proliferation and promotes apoptosis, which may occur via inhibition of the PI3K/Akt/ERK cascade. | 31081053 |
| 2018-10-13 10:03:00 | Results demonstrated thatHOXA6 is up-regulated in colorectal cancer (CRC) and promoted cell proliferation, migration and invasion, but inhibited apoptosis, whereas the downregulated expression of HOXA6 produced the opposite effects. HOXA6 regulated apoptosis through the Bcl-2 signaling pathway, and regulated migration and invasion through the EMT process. | 29620285 |
| 2014-07-19 11:33:00 | HOXA6 is a signature gene involved in cell growth and sensitivity to chemotherapy in acute myeloid leukemia cells. | 23539541 |
| 2013-07-27 10:05:00 | Data indicate that genes with hypermethylated CpG islands in malignant meningiomas, such as HOXA6 and HOXA9, tend to coincide with the binding sites of polycomb repressive complexes (PRC) in early developmental stage. | 23349797 |
| Type | IDs |
|---|---|
| Synonymous | HOX1, HOX1.2, HOX1B |
| Gene |
UniProtKB-ID:
HXA6_HUMAN
UniprotKB:
P31267
UniParc:
UPI000012CF32
EMBL:
CH236948,
BC104917,
AC004080,
BC104915,
BC069497,
CH471073
Ensembl:
ENSG00000106006
KO:
hsa:3203
|
| Nucleutide sequences |
EMBL-CDS:
AAI04918.1,
AAH69497.1,
AAI04916.1,
EAW93875.1,
EAL24222.1
Ensembl_TRS:
ENST00000222728
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000222728
RefSeq:
NP_076919.1
|
| Others |
UniRef100:
UniRef100_P31267
UniRef90:
UniRef90_P09092
UniRef50:
UniRef50_P09092
UniGene:
Hs.679517
CCDS:
CCDS5407.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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