| Type | Description |
|---|---|
| Definition | sperm flagellar 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:23:00 | Genetic interaction between central pair apparatus genes CFAP221, CFAP54, and SPEF2 in mouse models of primary ciliary dyskinesia. | 32704025 |
| 2020-02-08 11:37:00 | Mutations in SPEF2 are associated with multiple morphological abnormalities of the sperm flagella and primary ciliary dyskinesia. | 31942643 |
| 2017-09-30 11:50:00 | Investigated the function of SPEF2 during spermatogenesis using a male germ cell-specific Spef2 knockout model. In addition to defects in sperm tail development, we observed a duplication of the basal body and failure in manchette migration resulting in an abnormal head shape. | 28619825 |
| 2012-02-18 11:08:00 | Data indicate that SPEF2 is required for cilia function/motility; defect in SPEF2 results in primary ciliary dyskinesia. SPEF2 plays important role in spermatogenesis and sperm flagellum assembly. (base/AA sequence data submitted to GenBank) | 21715716 |
| 2010-06-14 11:43:00 | The crucial importance of SPEF2 in sperm differentiation and involvement of SPEF2 in structuring of the sperm tail. | 19889948 |
| Type | IDs |
|---|---|
| Synonymous | C230086A09Rik |
| Gene |
UniProtKB-ID:
SPEF2_MOUSE
UniprotKB:
Q8C9J3
UniParc:
UPI00000E9747,
UPI0003D6EAA3,
UPI0000354C68,
UPI000060744A
EMBL:
HQ856050,
BC132288,
BC132098,
AC133959,
AC133586,
AK041992
Ensembl:
ENSMUSG00000072663
KO:
mmu:320277
|
| Nucleutide sequences |
EMBL-CDS:
AAI32289.1,
AAI32099.1,
AEA11026.1,
BAC31126.1
Ensembl_TRS:
ENSMUST00000159368,
ENSMUST00000041840,
ENSMUST00000160236
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000124222,
ENSMUSP00000124723,
ENSMUSP00000035762
RefSeq:
NP_001291973.1,
XP_017172157.1,
NP_796097.2,
XP_017172156.1,
NP_001291971.1
|
| Others |
UniRef100:
UniRef100_Q8C9J3
UniRef90:
UniRef90_Q8C9J3
UniRef50:
UniRef50_Q8C9J3
UniGene:
Mm.127822
CCDS:
CCDS37041.1,
CCDS84163.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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