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320145 Sp8

320145

Sp8

trans-acting transcription factor 8

protein-coding

Mus musculus

基因描述

Type Description
Definition trans-acting transcription factor 8

研究结论

Date Results Publications
2020-09-26 13:07:00 Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. 31070778
2019-11-16 13:57:00 While Sp8 plays an early role in controlling proliferation in all lineages, it is not involved in the early specification of calretinin+ periglomerular interneurons, but plays a crucial role in their long term survival. 30266956
2019-11-16 10:54:00 our results demonstrate that Sp8 and Sp9 have crucial roles in regulating olfactory bulb interneuron development 28981617
2018-08-04 11:56:00 SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. 29967281
2016-09-03 10:52:00 Sp5/8 bind directly to GC boxes in Wnt target gene enhancers and to adjacent, or distally positioned, chromatin-bound T-cell factor (Tcf) 1/lymphoid enhancer factor (Lef) 1 to facilitate recruitment of beta-catenin to target gene enhancers. 26969725

名称对应

Type IDs
Synonymous D930049B17Rik, mBtd
Gene
UniProtKB-ID: SP8_MOUSE, Q5QR90_MOUSE
UniprotKB: Q8BMJ8, Q5QR90
UniParc: UPI00000EB310
EMBL: AJ844914, AK053093, AK030745
Ensembl: ENSMUSG00000048562
KO: mmu:320145
Nucleutide sequences
EMBL-CDS: BAC27113.1, BAC35264.1, CAH59969.1
Ensembl_TRS: ENSMUST00000063918
Protein sequencees
Ensembl_PRO: ENSMUSP00000065746
RefSeq: XP_011242426.1, XP_006516046.1, XP_006516050.1, XP_006516048.1, NP_001366309.1, NP_001366308.1, XP_006516051.1, NP_796056.2, XP_006516049.1
Others
UniRef100: UniRef100_Q8BMJ8
UniRef90: UniRef90_Q8BMJ8
UniRef50: UniRef50_Q8IXZ3
UniGene: Mm.51682
CCDS: CCDS26213.1

全选

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研究热度

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