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320024 Nceh1

320024

Nceh1

neutral cholesterol ester hydrolase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition neutral cholesterol ester hydrolase 1

研究结论

Date Results Publications
2015-10-17 10:59:00 These results suggest that Nceh1 plays a dominant role over Lipe in the hydrolysis of CE and subsequent cholesterol efflux in MPMs 24868095
2015-10-17 10:09:00 reducing the cholesteryl ester content of foam cells, Nceh1 may protect against the pro-apoptotic effect of oxysterols and modulate the development of atherosclerosis. 24891333
2012-04-07 10:27:00 Gender difference of atherogenesis is partly accounted for activation of neutral cholesterol ester hydrolase through estrogen-dependent translocation of A-kinase type II in macrophages. 21944698
2011-02-26 11:10:00 Nceh1 is involved in the adrenal cholesterol metabolism, and the cholesterol ester hydrolytic activity in adrenal glands is associated with the organ enlargement. 21111707
2010-03-22 11:07:00 NCEH is targeted to the ER of macrophages, where it hydrolyzes CE to deliver cholesterol for efflux out of the cells. 19592704

名称对应

Type IDs
Synonymous Aadacl1, B230106I24Rik, CPO-BP, Nceh
Gene
UniProtKB-ID: NCEH1_MOUSE
UniprotKB: Q8BLF1
UniParc: UPI00000EB470
EMBL: AK173158, AK034339, BC082569, AK045363, AK135837
Ensembl: ENSMUSG00000027698
KO: mmu:320024
Nucleutide sequences
EMBL-CDS: BAE22685.1, BAD32436.1, BAC28680.1, AAH82569.1, BAC32327.1
Ensembl_TRS: ENSMUST00000046515
Protein sequencees
Ensembl_PRO: ENSMUSP00000045864
RefSeq: NP_848887.1, XP_011247986.1
Others
UniRef100: UniRef100_Q8BLF1
UniRef90: UniRef90_Q8BLF1
UniRef50: UniRef50_Q8BLF1
UniGene: Mm.24576
CCDS: CCDS17271.1

全选

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研究热度

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