| Type | Description |
|---|---|
| Definition | UDP-glucose glycoprotein glucosyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:59:00 | UGGT1 retains proinsulin in the endoplasmic reticulum in an arginine dependent manner. | 32423812 |
| 2017-09-30 13:43:00 | Loss of UGT1 expression is associated with neonatal hyperbilirubinemia. | 28025333 |
| 2017-09-16 11:18:00 | Increased UGGT1 levels elevated viral growth rates, while viral pathogenicity was observed to be lower in heterozygous knockout mice (Uggt1 +/- mice). These findings provide important insight on the role of UPR and host UGGT1 in regulating RNA virus replication and pathogenicity. | 28545059 |
| 2014-03-22 11:55:00 | study demonstrates that UGGT1 enzymatic activity, in conjunction with lectin-like chaperones, helps to limit aggregation and polymer formation of misfolded glycoprotein substrates, decreasing their BiP association and ER stress | 23864712 |
| 2014-03-01 10:43:00 | the expression of two UGGT isoforms, UGGT1 and UGGT2 was demonstrated and both isoforms are active mouse hybridoma cells. | 24140206 |
| Type | IDs |
|---|---|
| Synonymous | 0910001L17Rik, A930007H10Rik, AA589501, AI414429, AI448372, C820010P03Rik, GT, UGT1, Ugcgl1 |
| Gene |
UniProtKB-ID:
UGGG1_MOUSE
UniprotKB:
Q6P5E4
UniParc:
UPI0001A4718A
EMBL:
AC133102,
BC062936,
BC068283
Ensembl:
ENSMUSG00000037470
KO:
mmu:320011
|
| Nucleutide sequences |
EMBL-CDS:
AAH68283.1,
AAH62936.1
Ensembl_TRS:
ENSMUST00000046875
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037930
RefSeq:
NP_942602.2,
XP_006496125.1
|
| Others |
UniRef100:
UniRef100_Q6P5E4
UniRef90:
UniRef90_Q6P5E4
UniRef50:
UniRef50_Q9JLA3
UniGene:
Mm.261022
CCDS:
CCDS48238.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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