| Type | Description |
|---|---|
| Definition | autism susceptibility candidate 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 12:03:00 | Description of a mouse mutation, T(5G2;8A1)GSO, a reciprocal translocation that breaks between Auts2 and Galnt17 and dysregulates both genes and Is associated with phenotypes related to the human AUTS2 syndrome. | 31554716 |
| 2017-09-09 13:32:00 | Study reveals AUTS2 signaling role in mediating heroin-induced behavioral and neurochemical adaptations in the nucleus accumbens, but not the caudate-putamen, potentially mediated through the control of Rac1 activity. | 27423627 |
| 2015-08-22 11:30:00 | Our results implicate Auts2 as an active regulator of important neurodevelopmental genes and pathways and identify novel genomic regions that could be associated with ASD and other neurodevelopmental diseases. | 25180570 |
| 2015-07-25 11:38:00 | AUTS2 activates Rac1 to induce lamellipodia but downregulates Cdc42 to suppress filopodia. | 25533347 |
| 2010-05-31 11:09:00 | Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology. | 19948250 |
| Type | IDs |
|---|---|
| Synonymous | 2700063G02Rik, A730011F23Rik, D830032G16Rik |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_001350409.1
|
| Others |
UniGene:
Mm.409595,
Mm.488992
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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