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319801 Tigar

319801

Tigar

Trp53 induced glycolysis repulatory phosphatase

protein-coding

Mus musculus

基因描述

Type Description
Definition Trp53 induced glycolysis repulatory phosphatase

研究结论

Date Results Publications
2021-03-27 14:43:00 TIGAR/AP-1 axis accelerates the division of Lgr5(-) reserve intestinal stem cells to reestablish intestinal architecture after lethal radiation. 32632140
2020-12-12 13:29:00 TIGAR reduces smooth muscle cell autophagy to prevent pulmonary hypertension. 32946259
2020-07-18 11:16:00 The study is the first to indicate that Wnt signaling activates TIGAR and protects SGNs against cisplatin-induced damage through the inhibition of oxidative stress and apoptosis in SGNs, and this might offer novel therapeutic targets for the prevention of SGN injury. 29587485
2020-06-27 12:40:00 The results suggest that p53-TIGAR metabolic axis-mediated glycolytic suppression may play a compensatory role in attenuating DNA damage and proliferative exhaustion in Fanconi Anemia hematopoietic stem cells. 30977208
2020-06-13 10:25:00 this study shows that TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury 30978385

名称对应

Type IDs
Synonymous 9630033F20Rik, AA793651, AI595337, C79710, C85509
Gene
UniProtKB-ID: TIGAR_MOUSE, B2RWB7_MOUSE
UniprotKB: Q8BZA9, B2RWB7
UniParc: UPI00000EA44B
EMBL: BC147718, AK036082, AK145896, AK163290, BC147705
Ensembl: ENSMUSG00000038028
KO: mmu:319801
Nucleutide sequences
EMBL-CDS: BAE37278.1, BAE26732.1, BAC29298.1, AAI47706.1, AAI47719.1
Ensembl_TRS: ENSMUST00000039913
Protein sequencees
Ensembl_PRO: ENSMUSP00000048643
RefSeq: NP_795977.1, XP_006506317.1
Others
UniRef100: UniRef100_Q8BZA9
UniRef90: UniRef90_Q8BZA9
UniRef50: UniRef50_Q8BZA9
UniGene: Mm.101836
CCDS: CCDS20563.1

全选

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研究热度

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