| Type | Description |
|---|---|
| Definition | hypoxia-inducible factor 1, alpha subunit inhibitor |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 11:26:00 | HIF1AN was confirmed as a direct target of miR-135-5p. [miR-135-5p] | 31410089 |
| 2015-08-15 10:09:00 | FIH-1 has a role in disrupting the LRRK1/EGFR complex to positively regulate keratinocyte migration | 25455687 |
| 2015-08-08 10:39:00 | miR-31/FIH1 pathway associates with liver fibrosis, perhaps by participation in the TGF-beta/Smad3 signalling of hepatic stellate cells. | 25728779 |
| 2013-09-21 12:39:00 | gankyrin binds to and sequester factor inhibiting hypoxia-inducible factor-1 (FIH-1), which results in decreased interaction between FIH-1 and hypoxia-inducible factor-1alpha (HIF-1alpha) and increased activity of HIF-1 to promote VEGF production. | 23376718 |
| 2012-12-22 11:15:00 | Our results define a previously unknown mechanism for keratinocyte fate decisions where Notch signaling potential is, in part, controlled through a miR-31/FIH-1 nexus. | 22891326 |
| Type | IDs |
|---|---|
| Synonymous | 2310046M24Rik, A830014H24Rik, FIH, FIH1 |
| Gene |
UniProtKB-ID:
HIF1N_MOUSE
UniprotKB:
Q8BLR9
UniParc:
UPI00006A77E8,
UPI0000022575
EMBL:
AK043636,
AK154774,
BC130013
Ensembl:
ENSMUSG00000036450
KO:
mmu:319594
|
| Nucleutide sequences |
EMBL-CDS:
BAE32822.1,
AAI30014.1,
BAC31602.1
Ensembl_TRS:
ENSMUST00000040455
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035326
RefSeq:
NP_795932.2
|
| Others |
UniRef100:
UniRef100_Q8BLR9
UniRef90:
UniRef90_Q9NWT6
UniRef50:
UniRef50_Q9NWT6
UniGene:
Mm.145278
CCDS:
CCDS29852.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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