| Type | Description |
|---|---|
| Definition | spectrin repeat containing, nuclear envelope 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:05:00 | Nesprins are mechanotransducers that discriminate epithelial-mesenchymal transition programs. | 32790861 |
| 2020-07-18 12:13:00 | Study found the lack of an overt retinal phenotype in Syne-2/Nesprin-2 KO mice suggests the usage of alternative translational start sites, producing Syne-2 splice variants with an intact Pcnt interaction site. | 31614616 |
| 2020-07-04 10:18:00 | Nesprin-2G knockout fibroblasts exhibit reduced migration, changes in focal adhesion composition, and reduced ability to generate traction forces. | 30667166 |
| 2019-11-30 11:44:00 | CRISPR/Cas9-mediated knockout of Syne-2 in cell culture led to an overexpression and mislocalization of Pcnt and to ciliogenesis defects. This suggests that the Pcnt-Syne-2 complex is important for ciliogenesis and outer segment formation during retinal development and plays a role in nuclear migration. | 30054381 |
| 2019-09-21 12:21:00 | The Nesprin-2 gene function is crucial during embryonic growth, differentiation and organogenesis. | 30220251 |
| Type | IDs |
|---|---|
| Synonymous | 6820443O06Rik, AW546258, Cpfl8, D12Ertd777e, KASH2, NUA, Nesp2g, dice, mKIAA1011 |
| Gene |
UniProtKB-ID:
SYNE2_MOUSE
UniprotKB:
Q6ZWQ0
UniParc:
UPI00004408C8,
UPI0001505BA1,
UPI00000040C8
EMBL:
AK052521,
AC164121,
AC159897,
BC082586,
AC166991,
AC115714
Ensembl:
ENSMUSG00000063450
KO:
mmu:319565
|
| Nucleutide sequences |
EMBL-CDS:
BAC35023.1,
AAH82586.1
Ensembl_TRS:
ENSMUST00000044217
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047697
RefSeq:
NP_001005510.2
|
| Others |
UniRef100:
UniRef100_Q6ZWQ0
UniRef90:
UniRef90_Q6ZWQ0
UniRef50:
UniRef50_Q8WXH0
UniGene:
Mm.26652
CCDS:
CCDS49091.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员