| Type | Description |
|---|---|
| Definition | integrin alpha 11 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 12:16:00 | integrin alpha11 pro-invasive activity relies on its ability to interact with PDGFRbeta in a ligand-dependent manner and to promote its downstream JNK activation, leading to the production of tenascin C, a pro-invasive matricellular protein. | 31287804 |
| 2020-04-25 10:38:00 | Data show that integrin alpha-11 (integrin alpha11) is a physiologically important receptor for Osteolectin, mediating its effect on osteogenesis. | 30632962 |
| 2019-07-20 11:31:00 | We report for the first time that overexpression of integrin alpha11 induces cardiac fibrosis and left ventricular hypertrophy | 28771943 |
| 2019-07-06 12:43:00 | Data show that stromal integrin alpha11-deficiency reduces interstitial fluid pressure and perturbs collagen structure in triple-negative breast xenograft indicating a new role for integrin alpha11beta1 in the tumor microenvironment. These results suggest that integrin alpha11beta1 has a pro-tumorigenic effect on triple-negative breast cancer growth in vivo. | 30876468 |
| 2017-07-08 11:59:00 | Deletion of ITGA11 in diabetic mice attenuates cardiac fibrosis progression but does not improve cardiac function. Impairments of cardiac function in null mice appear to be due to a novel role of ITGA11 in regulating cardiomyocyte growth and organization and myofibril development. | 27199132 |
| Type | IDs |
|---|---|
| Synonymous | 4732459H24Rik |
| Gene |
UniProtKB-ID:
Q8CE84_MOUSE,
A0A0B4J1F0_MOUSE,
Q7TQC3_MOUSE
UniprotKB:
Q8CE84,
A0A0B4J1F0,
Q7TQC3
UniParc:
UPI00001AE10D,
UPI00005AB5A1,
UPI000004914D
EMBL:
AC164614,
AY124460,
AK028821,
AC166097
Ensembl:
ENSMUSG00000032243
KO:
mmu:319480
|
| Nucleutide sequences |
EMBL-CDS:
BAC26137.2,
AAM62130.1
Ensembl_TRS:
ENSMUST00000034774
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034774
RefSeq:
XP_036010941.1,
NP_795896.4
|
| Others |
UniRef100:
UniRef100_Q7TQC3,
UniRef100_A0A0B4J1F0,
UniRef100_P61622
UniRef90:
UniRef90_P61622
UniRef50:
UniRef50_Q9UKX5
UniGene:
Mm.34883
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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