| Type | Description |
|---|---|
| Definition | complement component 5a receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:11:00 | Absence of the C5a Receptor C5aR2 Worsens Ischemic Tissue Injury by Increasing C5aR1-Mediated Neutrophil Infiltration. | 33028618 |
| 2020-06-06 11:00:00 | Growth of B16.F0 melanoma tumors was increased in C5aR2-/- mice. Analysis of tumor-infiltrating leukocyte populations showed no significant differences between wild-type and C5aR2-/- mice. | 31298935 |
| 2020-05-09 11:08:00 | C5aR2 transports tissue-derived C5a into the lumen of blood vessels to induce the initial arrest and adhesion of neutrophils, igniting a type III hypersensitivity reaction in the joint. | 31076525 |
| 2020-03-07 12:22:00 | C5aR1 augment disease pathology and are interesting targets for treatment of meningococcal sepsis. | 31274379 |
| 2019-06-29 11:30:00 | Taken together, this study shows distinct roles of C5aR1 and C5aR2 in a model of renal IRI with progressive renal fibrosis. Both C5aR1-/- and C5aR2-/- mouse strains, compared with WT mice, showed attenuated inflammation and fibrosis after IRI. | 29935951 |
| Type | IDs |
|---|---|
| Synonymous | C5L2, E030029A11Rik, Gpr77 |
| Gene |
UniProtKB-ID:
C5AR2_MOUSE,
E9PVQ2_MOUSE,
E9QQ21_MOUSE
UniprotKB:
Q8BW93,
E9PVQ2,
E9QQ21
UniParc:
UPI00003D7979,
UPI00000EA80B,
UPI0000D8A90F
EMBL:
AK053187,
BC145834,
AK160050,
BC137941,
AC156630
Ensembl:
ENSMUSG00000074361
KO:
mmu:319430
|
| Nucleutide sequences |
EMBL-CDS:
BAE35590.1,
AAI45835.1,
BAC35303.1,
AAI37942.1
Ensembl_TRS:
ENSMUST00000238927,
ENSMUST00000171425,
ENSMUST00000238893,
ENSMUST00000098792
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000133056,
ENSMUSP00000158951,
ENSMUSP00000159074,
ENSMUSP00000096389
RefSeq:
NP_001139477.2,
XP_006540117.1,
XP_006540116.1,
XP_006540118.1,
XP_006540112.2,
XP_006540115.1,
XP_011248896.1,
XP_036009056.1,
XP_006540120.2,
XP_006540119.1,
NP_795886.3
|
| Others |
UniRef100:
UniRef100_Q8BW93,
UniRef100_E9QQ21,
UniRef100_E9PVQ2
UniRef90:
UniRef90_Q8BW93
UniRef50:
UniRef50_Q695P6
UniGene:
Mm.239570
CCDS:
CCDS52036.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员