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319387 Adgrl3

319387

Adgrl3

adhesion G protein-coupled receptor L3

protein-coding

Mus musculus

基因描述

Type Description
Definition adhesion G protein-coupled receptor L3

研究结论

Date Results Publications
2020-06-13 13:03:00 Study further validates Adgrl3 constitutive knockout mice as an experimental model of attention deficit/hyperactivity disorder while providing neuroanatomical targets for future studies involving ADGRL3 modified models. 30849401
2020-04-11 12:34:00 Latrophilin-3 pancreatic variants couple to Gi proteins reducing cAMP. Latrophilin-3 activation in pancreatic islets reduces insulin secretion. 30726739
2016-09-10 10:27:00 Data show that Unc5 cell guidance receptor Unc5D controls Latrophilin3 (LPHN3)-FLRT protein FLRT2-mediated cell adhesion. 27091502
2016-07-02 10:56:00 The crystal structure of the OLF/FLRT3 complex shows that LPHN3-OLF in the closed state binds with high affinity to the concave face of FLRT3-LRR with a combination of hydrophobic and charged residues. 26235031
2013-04-13 11:29:00 Null mutant Lphn3 mice had a hyperactive phenotype in the open field test, independent of sex, and were more sensitive to locomotor stimulation. 22575564

名称对应

Type IDs
Synonymous 5430402I23Rik, CIRL-3, D130075K09Rik, Gm1379, LEC3, Lphn3, mKIAA0768
Gene
UniProtKB-ID: AGRL3_MOUSE, D3Z634_MOUSE, D3Z3X6_MOUSE, D3Z6H9_MOUSE
UniprotKB: Q80TS3, D3Z634, D3Z3X6, D3Z6H9
UniParc: UPI0001611804, UPI0000EADF3C, UPI00004B2BB1, UPI0001611816, UPI0000EADF3D, UPI0000EADF3A, UPI000161180C, UPI0000EADF3B, UPI0000EADF39
EMBL: AY255584, AC114425, AC104196, AK147374, AC121837, AK122367, AC114622, BC088989, AC102517, BC094668, AC122054, AC124825, BC058992, AC155075, AK145069
Ensembl: ENSMUSG00000037605
KO: mmu:319387
Nucleutide sequences
EMBL-CDS: AAH88989.1, BAE26219.1, AAH58992.1, BAC65649.1, AAH94668.1, AAO85096.1, BAE27870.1
Ensembl_TRS: ENSMUST00000072521, ENSMUST00000117407, ENSMUST00000122356, ENSMUST00000122037, ENSMUST00000118442, ENSMUST00000119385
Protein sequencees
Ensembl_PRO: ENSMUSP00000112388, ENSMUSP00000113600, ENSMUSP00000072336, ENSMUSP00000113374, ENSMUSP00000113836, ENSMUSP00000113243
RefSeq: XP_036021079.1, NP_001334297.1, XP_036021073.1, NP_001346759.1, XP_036021092.1, XP_036021072.1, XP_036021062.1, NP_941991.1, XP_036021076.1, XP_011247771.1, XP_036021063.1, XP_011247776.1, NP_001334296.1, NP_001334300.1, XP_036021074.1, XP_036021089.1, XP_036021077.1, XP_030110424.1, XP_011247773.1, XP_036021091.1, NP_001346757.1, NP_001346763.1, XP_036021085.1, XP_017176404.1, XP_036021075.1, XP_030110427.1, NP_001346762.1, XP_036021082.1, XP_036021093.1, XP_017176410.1, XP_036021067.1, XP_036021066.1, XP_011247763.1, XP_036021061.1, XP_036021065.1, NP_001334298.1, XP_036021094.1, NP_001346758.1, NP_001346761.1, XP_036021088.1, XP_036021069.1, XP_036021083.1, XP_017176408.1, XP_036021081.1, XP_036021086.1, XP_036021090.1, XP_036021068.1, XP_030110426.1, XP_036021064.1, XP_011247767.1, NP_001346760.1, XP_036021070.1, XP_036021084.1, XP_036021071.1, XP_036021087.1, XP_036021080.1, NP_001346755.1, XP_036021078.1
Others
UniRef100: UniRef100_D3Z634, UniRef100_D3Z6H9, UniRef100_Q80TS3, UniRef100_D3Z3X6
UniRef90: UniRef90_Q80TS3, UniRef90_Q80TS3-2
UniRef50: UniRef50_Q80TS3
UniGene: Mm.273631, Mm.461016
CCDS: CCDS84894.1, CCDS39122.1

全选

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