| Type | Description |
|---|---|
| Definition | secretin receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 10:33:00 | High secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early-stage primary biliary cholangitis. | 31251081 |
| 2020-03-21 11:54:00 | The involvement of secretin (SCT) and its receptor (SCTR) in angiotensin II (ANGII)-mediated osmoregulation by forming SCTR/ angiotensin II type 1 receptor (AT1R) heteromer is well established. In this study, we demonstrated that SCTR/AT1R complex can mediate ANGII-induced aldosterone secretion/release through potentiating calcium mobilization. | 31479491 |
| 2019-06-15 12:26:00 | Enhanced senescence levels in cholangiocytes from Mdr2(-/-) mice were reversed to normal in SR(-/-)/Mdr2(-/-) mice. | 29977037 |
| 2017-09-09 14:44:00 | Knockout of SCTR results in defective aldosterone biosynthesis/release and altered sensitivity of ENaCs to amiloride. | 28082350 |
| 2017-08-19 12:38:00 | Data show that upon heteromer formation with secretin receptor (SCTR), R137H, a nephrogenic diabetes insipidus (NDI)-causing vasopressin receptor 2 (AVPR2) mutant that is defective in trafficking to cell surface, can functionally be rescued. | 27649563 |
| Type | IDs |
|---|---|
| Synonymous | 6530402O03Rik |
| Gene |
UniProtKB-ID:
SCTR_MOUSE,
H7BX37_MOUSE
UniprotKB:
Q5FWI2,
H7BX37
UniParc:
UPI00004C95CE,
UPI0000F4CEF5
EMBL:
AY255623,
BC089355,
AC165443
Ensembl:
ENSMUSG00000026387
KO:
mmu:319229
|
| Nucleutide sequences |
EMBL-CDS:
AAO85135.1,
AAH89355.1
Ensembl_TRS:
ENSMUST00000189037,
ENSMUST00000072886
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000139932,
ENSMUSP00000072660
RefSeq:
XP_006529752.1,
XP_011246331.1,
XP_030110733.1,
NP_001012322.2,
XP_036021563.1,
XP_006529753.1,
XP_036021564.1,
XP_011246333.1,
XP_036021561.1,
XP_036021562.1,
XP_006529749.1,
XP_006529751.1,
XP_006529747.1,
NP_001298006.1
|
| Others |
UniRef100:
UniRef100_Q5FWI2,
UniRef100_H7BX37
UniRef90:
UniRef90_H7BX37,
UniRef90_Q5FWI2
UniRef50:
UniRef50_Q5FWI2
UniGene:
Mm.189223
CCDS:
CCDS78668.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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