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3185 HNRNPF

3185

HNRNPF

heterogeneous nuclear ribonucleoprotein F

protein-coding

Homo sapiens

基因描述

Type Description
Definition heterogeneous nuclear ribonucleoprotein F

研究结论

Date Results Publications
2020-02-22 12:46:00 Study in thyroid cancer series enriched with poor prognosis cases and found hsa-miR139-5p downregulation as a bona fide poor-prognostic factor. Exogenous hsa-miR-139-5p expression repressed procancer features of thyroid cancer cells. Proteomic analysis revealed that the alternative splicing factor HNRNPF is a putative hsa-miR-139-5p. 31403184
2020-01-11 10:41:00 The overexpression of hnRNP-F caused an increase in the stability of Snail1 mRNA. Our RNA chip analysis revealed that hnRNP-F could combine with Snail1 mRNA, and we further demonstrated that hnRNP-F could directly bind to the 3' untranslated region of Snail1 mRNA to enhance its stability. 31221586
2019-09-14 10:51:00 this study is the first to identify hnRNP F/H and K as regulators of Mcl-1 alternative splicing. 30468106
2019-08-17 11:30:00 Binding of the hnRNP F to the YAP 3'UTR was demonstrated by Cross-linked RNA Immunoprecipitation. hnRNP F and hnRNP U negatively regulate YAP expression. 30312683
2019-01-19 11:44:00 FOXP3 represses the ability of hnRNPF to bind to its target pre-mRNA and thus modulates RNA alternative splicing 29773655

名称对应

Type IDs
Synonymous HNRPF, OK/SW-cl.23, mcs94-1
Gene
UniProtKB-ID: HNRPF_HUMAN, A0A024R7T3_HUMAN
UniprotKB: P52597, A0A024R7T3
UniParc: UPI0000000C5C
EMBL: BC004254, CH471160, BC016736, L28010, AL512654, BC015580, BC001432, AK001364, BC106008
Ensembl: ENSG00000169813
KO: hsa:3185
Nucleutide sequences
EMBL-CDS: AAI06009.1, AAH16736.1, AAH15580.1, BAG50896.1, AAH01432.1, AAH04254.1, AAC37584.1, EAW86595.1, EAW86597.1, EAW86598.1, EAW86596.1, EAW86599.1
Gene_ORFName: hCG_1770443
Ensembl_TRS: ENST00000337970, ENST00000357065, ENST00000443950, ENST00000356053, ENST00000544000
Protein sequencees
Ensembl_PRO: ENSP00000348345, ENSP00000338477, ENSP00000349573, ENSP00000400433, ENSP00000438061
RefSeq: NP_001091675.1, NP_001091677.1, NP_001091676.1, NP_001091678.1, NP_001091674.1, NP_004957.1
Others
UniRef100: UniRef100_P52597
UniRef90: UniRef90_P52597
UniRef50: UniRef50_P52597
UniGene: Hs.808, Hs.712955
CCDS: CCDS7204.1

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