| Type | Description |
|---|---|
| Definition | nudix hydrolase 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:18:00 | NUDT2 is a novel complex formation enhancing factor regulating mTORC1-Rag GTPase signaling that is crucial for cell growth control. | 28089905 |
| 2017-07-22 13:24:00 | Regulation of gene expression is one of several roles proposed for the stress-induced nucleotide diadenosine tetraphosphate (Ap4A). We have examined this directly by a comparative RNA-Seq analysis of KBM-7 chronic myelogenous leukemia cells and KBM-7 cells in which the NUDT2 Ap4A hydrolase gene had been disrupted (NuKO cells), causing a 175-fold increase in intracellular Ap4A. | 27144453 |
| 2013-09-21 12:30:00 | This paper presents the crystal structure of wild-type and E58A mutant human Ap4A hydrolase. | 23384440 |
| 2011-04-23 10:20:00 | High NUDT2 is associated with breast carcinoma. | 20533549 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| Type | IDs |
|---|---|
| Synonymous | APAH1 |
| Gene |
UniProtKB-ID:
AP4A_HUMAN
UniprotKB:
P50583
UniParc:
UPI000013E431
EMBL:
BC004926,
U30313,
AL356494,
CH471071
Ensembl:
ENSG00000164978
KO:
hsa:318
|
| Nucleutide sequences |
EMBL-CDS:
EAW58463.1,
EAW58461.1,
AAC50277.1,
AAH04926.1,
EAW58462.1
Ensembl_TRS:
ENST00000379158,
ENST00000379155,
ENST00000618590,
ENST00000346365
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368452,
ENSP00000482384,
ENSP00000368455,
ENSP00000344187
RefSeq:
NP_671702.1,
NP_001231319.1,
NP_001152.1,
NP_671701.1,
XP_024303296.1
|
| Others |
UniRef100:
UniRef100_P50583
UniRef90:
UniRef90_P50583
UniRef50:
UniRef50_P50583
UniGene:
Hs.493767,
Hs.731743
CCDS:
CCDS6552.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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