| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4E family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-17 11:03:00 | We performed bioinformatics analyses of ESTs and the 3'UTRs of the main transcript splice variants of the translational initiation factor eIF4E1 and its family members, eIF4E2 and eIF4E3. We propose to elucidate the minor splice variants of eIF4E2 and eIF4E3 in great detail because they might produce proteins with modified features that fulfill different cellular roles from their major counterparts. | 28942592 |
| 2017-09-16 10:40:00 | Following heat shock, eIF4E2 is found in both processing bodies and stress granules, whereas eIF4E3_A relocates only to stress granules. | 27578149 |
| 2015-12-12 11:16:00 | MNK1 and MNK2 inhibition ablates eIF4E1 phosphorylation and concurrently enhances eIF4E3 expression in diffuse large B-cell lymphoma. | 25403230 |
| 2013-11-16 11:15:00 | eIF4E3 impedes oncogenic transformation and its expression is lost in some cancers. | 23587918 |
| Type | IDs |
|---|---|
| Synonymous | eIF-4E3, eIF4E-3 |
| Gene |
UniProtKB-ID:
IF4E3_HUMAN
UniprotKB:
Q8N5X7
UniParc:
UPI00015887BF,
UPI0000072CDF
EMBL:
AK126999,
BC068443,
BC031289,
AC134770,
AK313656
Ensembl:
ENSG00000163412
KO:
hsa:317649
|
| Nucleutide sequences |
EMBL-CDS:
BAG36410.1,
BAG54418.1,
AAH31289.3,
AAH68443.1
Ensembl_TRS:
ENST00000421769,
ENST00000448225,
ENST00000425534,
ENST00000389826,
ENST00000295612
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000295612,
ENSP00000411762,
ENSP00000393324,
ENSP00000410350,
ENSP00000374476
RefSeq:
NP_001269815.1,
NP_001128122.1,
XP_016861771.1,
NP_775495.1,
NP_001128123.1,
NP_001128121.1,
XP_011531953.1
|
| Others |
UniRef100:
UniRef100_Q8N5X7
UniRef90:
UniRef90_Q8N5X7
UniRef50:
UniRef50_Q9DBB5
UniGene:
Hs.581355
CCDS:
CCDS46867.1,
CCDS33786.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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