Kdm5c - lysine demethylase 5C-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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317432 Kdm5c

基因描述

Type	Description
Definition	lysine demethylase 5C

名称对应

Type	IDs
Synonymous	RGD1560601
Gene	UniProtKB-ID: V9GW19_RAT UniprotKB: V9GW19 UniParc: UPI0000DA45D0 EMBL: GAPM01000004 KO: rno:317432
Nucleutide sequences	EMBL-CDS: JAB84471.1
Protein sequencees	RefSeq: XP_008756613.1, XP_006227368.1, XP_008771368.1, XP_006227366.1, XP_006227367.1, XP_001064297.1
Others	UniRef100: UniRef100_V9GW19 UniRef90: UniRef90_V9GW19 UniRef50: UniRef50_P41229

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
28262558	Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. Cell Chem Biol Anthony Tumber , Andrea Nuzzi , Edward S Hookway , Stephanie B Hatch , Srikannathasan Velupillai , Catrine Johansson , Akane Kawamura , Pavel Savitsky , Clarence Yapp , Aleksandra Szykowska , Na Wu , Chas Bountra , Claire Strain-Damerell , Nicola A Burgess-Brown , Gian Filippo Ruda , Oleg Fedorov , Shonagh Munro , Katherine S England , Radoslaw P Nowak , Christopher J Schofield , Nicholas B La Thangue , Charlotte Pawlyn , Faith Davies , Gareth Morgan , Nick Athanasou , Susanne MÃ¼ller , Udo Oppermann , Paul E Brennan	2017-03-16	-
27214403	Structural analysis of human KDM5B guides histone demethylase inhibitor development. Nat Chem Biol Catrine Johansson , Srikannathasan Velupillai , Anthony Tumber , Aleksandra Szykowska , Edward S Hookway , Radoslaw P Nowak , Claire Strain-Damerell , Carina Gileadi , Martin Philpott , Nicola Burgess-Brown , Na Wu , Jola Kopec , Andrea Nuzzi , Holger Steuber , Ursula Egner , Volker Badock , Shonagh Munro , Nicholas B LaThangue , Sue Westaway , Jack Brown , Nick Athanasou , Rab Prinjha , Paul E Brennan , Udo Oppermann	2016-07-01	-
23932495	Prenatal MAM administration affects histone H3 methylation in postnatal life in the rat medial prefrontal cortex. Eur Neuropsychopharmacol Marzena MaÄkowiak , Ewelina Bator , Joachim Latusz , Patrycja Mordalska , Krzysztof WÄdzony	2014-02-01	-
23872847	Targeting H3K4 trimethylation in Huntington disease. Proc. Natl. Acad. Sci. U.S.A. Malini Vashishtha , Christopher W Ng , Ferah Yildirim , Theresa A Gipson , Ian H Kratter , Laszlo Bodai , Wan Song , Alice Lau , Adam Labadorf , Annie Vogel-Ciernia , Juan Troncosco , Christopher A Ross , Gillian P Bates , Dimitri Krainc , Ghazaleh Sadri-Vakili , Steven Finkbeiner , J Lawrence Marsh , David E Housman , Ernest Fraenkel , Leslie M Thompson	2013-08-06	-
23246292	A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARX. Am. J. Hum. Genet. Loredana Poeta , Francesca Fusco , Denise Drongitis , Cheryl Shoubridge , Genesia Manganelli , Stefania Filosa , Mariateresa Paciolla , Monica Courtney , Patrick Collombat , Maria Brigida Lioi , Jozef Gecz , Matilde Valeria Ursini , Maria Giuseppina Miano	2013-01-10	-
23200123	Histone lysine methylation dynamics: establishment, regulation, and biological impact. Mol. Cell Joshua C Black , Capucine Van Rechem , Johnathan R Whetstine	2012-11-30	Kdm6a, Kmt2d, Prdm16, Kdm4dl1, LOC100909949, LOC100911180, Kmt2b, Jmjd1c, Smyd2, Whsc1l1, Smyd1, Kdm4c, Kdm4b, Kdm2b, Kdm5b, Prdm8, Nsd1, Phf2, Kdm1b, Prdm6, Kmt5c, Kdm8, Ash1l, Kmt2e, Ezh2, Kdm3a, Kdm5a, Kdm4a, Prdm2, Kmt2a, Setd2, Phf8, Kdm5c, Kmt5b, Kdm2a, Ehmt2, Ehmt1, Dot1l, Kdm6b, Suv39h2, Prdm9, Smyd3, Kdm1a, Kmt2c, Kdm3b, Kdm7a, Setd7
22035299	Genetic pathways involved in carcinogenesis of clear cell renal cell carcinoma: genomics towards personalized medicine. BJU Int. FranÃ§ois Audenet , David R Yates , GÃ©raldine Cancel-Tassin , Olivier Cussenot , Morgan RouprÃªt	2012-06-01	Kdm6a, Vhl, Pbrm1, Setd2, Kdm5c
22326837	A novel c.2TÂ >Â C mutation of the KDM5C/JARID1C gene in one large family with X-linked intellectual disability. Eur J Med Genet Katrin Ounap , Helen Puusepp-Benazzouz , Maire Peters , Ulvi Vaher , Reet Rein , Anne Proos , Mike Field , Tiia Reimand	2012-03-01	Kdm5c, KDM5C
22199269	Histone-modifier gene expression profiles are associated with pathological and clinical outcomes in human breast cancer. Anticancer Res Neill Patani , Wen G Jiang , Robert F Newbold , Kefah Mokbel	2011-12-01	-
21960634	Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock. Science Luciano DiTacchio , Hiep D Le , Christopher Vollmers , Megumi Hatori , Michael Witcher , Julie Secombe , Satchidananda Panda	2011-09-30	Arntl, Clock, Kdm5c, Kdm5a, Hdac1, Kdm5b, per, tim, lid, Clk, cry, ARNTL, KDM5A, CLOCK

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