| Type | Description |
|---|---|
| Definition | apoptotic peptidase activating factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | Hypoxia-induced up-regulation of miR-27a promotes paclitaxel resistance in ovarian cancer. | 32190895 |
| 2020-12-12 13:23:00 | Long Hypoxia-Inducible Factor-1 1 Regulates Vascular Smooth Muscle Cells to Promote the Development of Thoracic Aortic Aneurysm by Modulating Apoptotic Protease-Activating Factor 1 and Targeting let-7g. | 32653692 |
| 2020-05-16 11:34:00 | Silencing of APAF1 reduced the sensitivity of bladder cancer cells to cisplatin chemotherapy. Furthermore, Circular RNA Cdr1as could directly sponge miR-1270 and abolish its effect on APAF1. | 31131537 |
| 2020-03-14 10:57:00 | A novel mechanism has been revealed that EV71 utilizes for virus release via a 3C protease-hnRNPA1-apaf1-caspase-3-apoptosis axis. | 31498791 |
| 2020-02-29 11:32:00 | These results show that ubiquitinated Apaf-1 may activate caspase-9 under conditions of proteasome impairment. | 31329620 |
| Type | IDs |
|---|---|
| Synonymous | APAF-1, CED4 |
| Gene |
UniProtKB-ID:
APAF_HUMAN
UniprotKB:
O14727
UniParc:
UPI00001A3E21,
UPI000002A3D9,
UPI0000036328,
UPI000002A3DA,
UPI000002A3DB,
UPI000002A3D8
EMBL:
CH471054,
AB103079,
BC136531,
AJ243008,
AJ243003,
AJ243006,
AJ243007,
AJ243048,
AJ243010,
AJ133645,
BC136532,
AF248734,
AJ243107,
AJ133644,
AJ243009,
AB007873,
AJ243004,
AJ243005,
AF013263,
AF149794,
AJ243011,
AJ133643,
AF134397
Ensembl:
ENSG00000120868
KO:
hsa:317
|
| Nucleutide sequences |
EMBL-CDS:
CAB55587.1,
AAK28401.1,
CAB65087.1,
AAI36532.1,
CAB55580.1,
CAB56462.1,
AAD34016.1,
AAI36533.1,
CAB55583.1,
CAB55588.1,
BAC77343.1,
CAB55579.1,
AAD38344.1,
CAB55582.1,
CAB65086.1,
AAC51678.1,
CAB55584.1,
CAB55585.1,
CAB55581.1,
EAW97606.1,
CAB55586.1,
BAA24843.2,
CAB65085.1
Ensembl_TRS:
ENST00000547045,
ENST00000359972,
ENST00000551964,
ENST00000550527,
ENST00000357310,
ENST00000552268,
ENST00000333991
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000448449,
ENSP00000448165,
ENSP00000334558,
ENSP00000448826,
ENSP00000349862,
ENSP00000449791,
ENSP00000353059
RefSeq:
NP_001151.1,
NP_863659.1,
NP_037361.1,
XP_016874739.1,
NP_863658.1,
NP_863651.1
|
| Others |
UniRef100:
UniRef100_O14727
UniRef90:
UniRef90_O14727
UniRef50:
UniRef50_O14727
UniGene:
Hs.552567
CCDS:
CCDS9070.1,
CCDS9069.1,
CCDS55863.1,
CCDS9071.1,
CCDS55862.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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