| Type | Description |
|---|---|
| Definition | BRCA1/BRCA2-containing complex, subunit 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 12:30:00 | BRCC3 expressed in oligodendrocyte precursor cells in vitro is required for the oligodendrocyte lineage progression toward the mature stage. Lack of BRCC3 function could deteriorate demyelination at the lesion site. An increase in Lys63-linked ubiquitination levels induced by the deregulation of BRCC3 expression promotes the endosomal/lysosomal processing of myelin proteins. | 31184779 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
BRCC3_RAT
UniprotKB:
B2RYM5
UniParc:
UPI000017FF2E
EMBL:
BC166833,
CH474092
Ensembl:
ENSRNOG00000048061
KO:
rno:316794
|
| Nucleutide sequences |
EMBL-CDS:
AAI66833.1,
EDL83574.1
Ensembl_TRS:
ENSRNOT00000071068
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000066438
RefSeq:
NP_001120772.1
|
| Others |
UniRef100:
UniRef100_B2RYM5
UniRef90:
UniRef90_B2RYM5
UniRef50:
UniRef50_P46736
UniGene:
Rn.52727
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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