| Type | Description |
|---|---|
| Definition | brinker |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 12:42:00 | Molecular Dynamics Simulations indicate that Brinker binds to its cognate DNA and folds in approximately 50 mus by an induced fit mechanism, acquiring most of its stable secondary and tertiary structure only after it reaches the final binding site on the DNA. | 29990433 |
| 2017-03-25 11:41:00 | we identify key roles for the Zelda and Zerknullt transcription factors in establishing the resulting expression domain, and find widespread binding of insulator proteins to the Mad and Brinker-bound genomic regions. Analysis of embryos lacking the BEAF-32 insulator protein shows reduced transcription of a peak BMP target gene and a reduction in the number of amnioserosa cells, the fate specified by peak BMP signaling. | 27379389 |
| 2014-05-03 11:59:00 | This work found that mutating the silencer elements in the brk locus results in an expansion of the brk expression domain. However, repression could still be observed in regions of maximal Dpp levels. | 23951114 |
| 2013-12-14 11:26:00 | although the recruitment of Gro is necessary and can be sufficient for Brk to make an almost morphologically wild-type fly, it is insufficient during oogenesis, where Brk must utilize CtBP and 3R to pattern the egg shell appropriately. | 24086079 |
| 2013-12-14 10:38:00 | here we investigate the cis-regulatory system controlling brinker (brk) expression in the Drosophila embryo. | 24044892 |
| Type | IDs |
|---|---|
| Synonymous | BRK, Brk, CG9653, Dm brk, Dmel\CG9653, ssg-1 |
| Gene |
UniProtKB-ID:
Q9XTN4_DROME
UniprotKB:
Q9XTN4
UniParc:
UPI000007D0BC
EMBL:
AF125986,
AB023583,
BT053738,
AE014298
EnsemblGenome:
FBgn0024250
KO:
dme:Dmel_CG9653
|
| Nucleutide sequences |
EMBL-CDS:
ACK77656.1,
AAD22080.1,
BAA76710.1,
AAF46251.3
Gene_ORFName:
Dmel_CG9653,
CG9653
EnsemblGenome_TRS:
FBtr0071048
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0071007
RefSeq:
NP_511069.3
|
| Others |
UniRef100:
UniRef100_Q9XTN4
UniRef90:
UniRef90_Q9XTN4
UniRef50:
UniRef50_Q9XTN4
UniGene:
Dm.4389
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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