| Type | Description |
|---|---|
| Definition | shifted |
| Date | Results | Publications |
|---|---|---|
| 2014-03-22 11:05:00 | We show that production of this PGC attractant depends upon shf as well as a second hh pathway gene g gamma1. | 24068944 |
| 2013-05-18 11:37:00 | analysis of balancing between hedgehog, a retention and release equilibrium given by Dally, Ihog, Boi and shifted/DmWif | 23276604 |
| 2012-12-08 10:02:00 | study concludes that the WIF domain is responsible for the divergence between Drosophila Shf and human Wif-1, channeling the recognition either toward Hh or Wg signal, whereas the EGF repeats give the protein the ability to interact with glypicans | 22951645 |
| 2010-01-21 00:00:00 | Shifted is a secreted protein that acts over a long distance and is required for the normal accumulation of Hh protein and its movement in the wing. | 15691766 |
| 2010-01-21 00:00:00 | Shf is the ortholog of the human Wnt inhibitory factor (WIF), a secreted antagonist of the Wingless pathway. Shf is required for Hh stability and for lipid-modified Hh diffusion. | 15691765 |
| Type | IDs |
|---|---|
| Synonymous | CG3134, CG3135, CT10514, D-Wif, DmWIF, DmWif, Dmel\CG3135, Shf, shf-ov |
| Gene |
UniProtKB-ID:
WIF1_DROME,
X2JCU9_DROME,
X2JED7_DROME,
X2JAQ0_DROME
UniprotKB:
Q9W3W5,
X2JCU9,
X2JED7,
X2JAQ0
UniParc:
UPI000007A04F,
UPI0002B8CE66,
UPI0002B8CDB1,
UPI0002B8CDF7
EMBL:
AE014298,
AY051622
EnsemblGenome:
FBgn0003390
KO:
dme:Dmel_CG3135
|
| Nucleutide sequences |
EMBL-CDS:
AAK93046.1,
AAF46198.2,
AHN59436.1,
AHN59434.1,
AHN59435.1
Gene_ORFName:
CG3135,
CG3135,
Dmel_CG3135,
CG3135,
Dmel_CG3135,
Dmel_CG3135,
CG3135
EnsemblGenome_TRS:
FBtr0070978,
FBtr0340090,
FBtr0340088,
FBtr0340089
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0070939,
FBpp0309089,
FBpp0309087,
FBpp0309088
RefSeq:
NP_001284964.1,
NP_001284963.1,
NP_001284965.1,
NP_572349.1
|
| Others |
UniRef100:
UniRef100_Q9W3W5,
UniRef100_X2JCU9,
UniRef100_X2JED7,
UniRef100_X2JAQ0
UniRef90:
UniRef90_Q9W3W5
UniRef50:
UniRef50_Q9W3W5
UniGene:
Dm.58
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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