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3160803 HN

3160803

HN

hemagglutinin-neuraminidase protein

protein-coding

基因描述

Type Description
Definition hemagglutinin-neuraminidase protein

研究结论

Date Results Publications
2017-05-13 11:13:00 Here, the authors have identified the flexible loop region connecting the bulky enzymatically active head and the four-helix bundle stalk to be essential for fusion promotion. 27489276
2014-06-28 11:50:00 Hydrophobic residues of the PIV5 HN stalk domain are crucial for F activation. 24453369
2014-03-22 10:37:00 The structure supports a model in which the heads of HN transition from down to up upon receptor binding thereby releasing steric constraints and facilitating the interaction between critical HN-stalk residues and F. 23950713
2012-01-28 12:16:00 The authors found a correlation between the position of the N-glycosylation mutants on the stalk structure and their neuraminidase activities as well as their abilities to promote fusion. 21994464
2010-10-23 10:18:00 E37D or E37K mutation shown to impair or abolish HN internalization. 20684967

名称对应

Type IDs
Gene
UniProtKB-ID: W5QKJ1_9MONO
UniprotKB: W5QKJ1
UniParc: UPI000012C583
EMBL: JQ743318
KO: vg:3160803
Nucleutide sequences
EMBL-CDS: AFE48450.1
Protein sequencees
RefSeq: YP_138517.1
Others
UniRef100: UniRef100_P04850
UniRef90: UniRef90_P04850
UniRef50: UniRef50_P04850

全选

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研究热度

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