F - fusion protein-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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3160801 F

基因描述

Type	Description
Definition	fusion protein

研究结论

Date	Results	Publications
2017-08-12 12:25:00	The S443D mutation destabilizes prefusion F proteins by disrupting a hydrogen bond network at the base of the F-protein globular head. The introduction of a P22L mutation robustly rescues destabilized F proteins through a local hydrophobic interaction between the N-terminal helix and a hydrophobic pocket.	27335462
2015-05-30 13:31:00	The P22 stabilizing site of F protein appears to act through a local conformational change and a hydrophobic pocket interaction.	25589638
2014-08-23 10:53:00	Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting.	24927585
2014-06-28 12:45:00	Hydrophobic residues of the PIV5 HN stalk domain are crucial for F activation.	24453369
2014-02-08 11:23:00	AN immunoglobulin-like domain on the PIV5 F protein mediates F and HN protein interactions.	24089572

名称对应

Type	IDs
Gene
Nucleutide sequences
Protein sequencees	RefSeq: YP_138515.1
Others

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
27335462	Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins. Proc. Natl. Acad. Sci. U.S.A. Albert S Song , Taylor A Poor , Luciano A Abriata , Theodore S Jardetzky , Matteo Dal Peraro , Robert A Lamb	2016-07-05	-
25589638	On the stability of parainfluenza virus 5 F proteins. J. Virol. Taylor A Poor , Albert S Song , Brett D Welch , Christopher A Kors , Theodore S Jardetzky , Robert A Lamb	2015-03-01	F
24927585	Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting. Proc. Natl. Acad. Sci. U.S.A. Taylor A Poor , Lisa M Jones , Amika Sood , George P Leser , Manolo D Plasencia , Don L Rempel , Theodore S Jardetzky , Robert J Woods , Michael L Gross , Robert A Lamb	2014-06-24	-
24453369	Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells. J. Virol. Sayantan Bose , Albert S Song , Theodore S Jardetzky , Robert A Lamb	2014-04-01	F, HN, HN, F
24089572	Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability. J. Virol. Sayantan Bose , Carissa M Heath , Priya A Shah , Maher Alayyoubi , Theodore S Jardetzky , Robert A Lamb	2013-12-01	-
23785199	Point mutations in the paramyxovirus F protein that enhance fusion activity shift the mechanism of complement-mediated virus neutralization. J. Virol. John B Johnson , Anthony P Schmitt , Griffith D Parks	2013-08-01	F
23183373	Membrane-dependent conformation, dynamics, and lipid interactions of the fusion peptide of the paramyxovirus PIV5 from solid-state NMR. J. Mol. Biol. Hongwei Yao , Mei Hong	2013-02-08	F
23012473	Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein. Proc. Natl. Acad. Sci. U.S.A. Brett D Welch , Yuanyuan Liu , Christopher A Kors , George P Leser , Theodore S Jardetzky , Robert A Lamb	2012-10-09	-
22171273	The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit. J. Virol. Aarohi Zokarkar , Robert A Lamb	2012-03-01	F
18667520	A hyperfusogenic F protein enhances the oncolytic potency of a paramyxovirus simian virus 5 P/V mutant without compromising sensitivity to type I interferon. J Virol Maria D Gainey , Mary J Manuse , Griffith D Parks	2008-10-01	-

研究热度

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