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3160800 V/P

3160800

V/P

V protein;phosphoprotein

protein-coding

基因描述

Type Description
Definition V protein;phosphoprotein

研究结论

Date Results Publications
2013-02-23 11:19:00 crystal structure of the MDA5 ATP-hydrolysis domain in complex with parainfluenzavirus 5 V protein; the V protein unfolded the ATP-hydrolysis domain of MDA5 and recognized a structural motif of MDA5 normally buried in the helicase fold leading to disruption of MDA5 ATP-hydrolysis site and prevention of RNA-bound MDA5 filament formation 23328395
2012-11-24 10:14:00 Using mass spectrometry analysis, the threonine residue at position 286 of P of parain fl uenza virus 5 was found phosphorylated. The phosphorylation site within the P protein has been found to play a positive role in viral mRNA synthesis and virus growth. 21680523
2012-06-16 10:41:00 Paramyxovirus 5 V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon beta induction. 22301134
2011-11-05 11:11:00 The authors propose that sumoylation of the P protein at K254 regulates parainfluenza virus 5 gene expression through a host protein. 21795356
2010-01-21 00:00:00 findings indicate that the V protein played a role in inhibiting IL-6 transcription in PIV5 infected cells 17692882

名称对应

Type IDs
Gene
UniProtKB-ID: W5QKN2_9MONO, W5QKJ0_9MONO
UniprotKB: W5QKN2, W5QKJ0
UniParc: UPI0000134B80, UPI0000138E97
EMBL: JQ743318, JQ743323
KO: vg:3160800
Nucleutide sequences
EMBL-CDS: AFE48484.1, AFE48446.1, AFE48445.1
Protein sequencees
RefSeq: YP_138513.1, YP_138512.1
Others
UniRef100: UniRef100_P11207, UniRef100_P11208
UniRef90: UniRef90_P11207, UniRef90_P11208
UniRef50: UniRef50_P11208, UniRef50_P11207

全选

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研究热度

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