| Type | Description |
|---|---|
| Definition | Mitochondrial assembly regulatory factor |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 11:52:00 | Depletion of Mitofusin (dMfn) or Opa1 led to dysfunctional mitochondria, activation of Target of rapamycin (TOR) and a marked accumulation of lipid droplets. Enhancement of lipid utilization by the mitochondria attenuated TOR activation and rescued the loss of GSCs that was caused by inhibition of mitochondrial fusion. | 31160709 |
| 2019-05-18 10:31:00 | both dominant negative and dominant active forms of mitofusin can cause Charcot-Marie-Tooth disease type 2A-associated defects. | 29898954 |
| 2019-01-26 10:46:00 | binds cyclin A mRNA and shortens its poly-A tail to reduce Cyclin A protein level during oocyte maturation | 30279526 |
| 2017-11-18 10:45:00 | Enhancing the profusion gene mitofusin/marf is beneficial in an in vivo model of TDP-43 proteinopathies, serving as a potential therapeutic target. | 28324764 |
| 2017-09-23 10:59:00 | activation of endoplasmic reticulum stress by defective mitochondria is neurotoxic in pink1 and parkin flies and that the reduction of this signalling is neuroprotective, independently of defective mitochondria. | 27336715 |
| Type | IDs |
|---|---|
| Synonymous | CG3869, CG38869, Dmel\CG3869, MARF, MFN2, Marf-1, Mfn, Mfn-2, anon-WO0125274.3, dMFN, dMfn, dMfn2, dmfn, marf, mfn, mfn2 |
| Gene |
UniProtKB-ID:
MARF_DROME
UniprotKB:
Q7YU24
UniParc:
UPI000358FE06,
UPI00001B98B2
EMBL:
AF355475,
AY095019,
BT010027,
AE014298
EnsemblGenome:
FBgn0029870
KO:
dme:Dmel_CG3869
|
| Nucleutide sequences |
EMBL-CDS:
AAQ22496.1,
AAS65267.2,
AAM11347.2,
AAM00196.1,
AAF46162.2
Gene_ORFName:
CG3869
EnsemblGenome_TRS:
FBtr0343373,
FBtr0070909,
FBtr0070910
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0089221,
FBpp0310030,
FBpp0089222
RefSeq:
NP_996358.2,
NP_572320.2,
NP_996357.1
|
| Others |
UniRef100:
UniRef100_Q7YU24
UniRef90:
UniRef90_Q7YU24
UniRef50:
UniRef50_Q7YU24
UniGene:
Dm.11038
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员