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315707 Csk

315707

Csk

C-terminal Src kinase

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition C-terminal Src kinase

研究结论

Date Results Publications
2018-02-24 10:14:00 recruitment of Csk and PTEN to the region between residues 266 and 283 within the C-terminus of Cx43 leads to c-Src inhibition in glioma cells and astrocytes 27391443
2018-02-10 11:53:00 Ang II increased Csk expression and induced podocyte apoptosis, stimulated Csk translocation and binding to Caveolin-1. 27225249
2013-08-10 10:36:00 an allosteric connection between Cbp binding and Csk activation that arises from residues in the betaB/betaC loop of the SH2 domain. 23548896
2011-11-26 11:25:00 Recognition of Src-family kinases (SFKs) by Csk is mainly governed by interactions between motifs located distally from the active site of Csk and determinants spatially separate from the carboxyl-terminal regulatory tyrosine residue in SFKs. 21699177
2010-01-21 00:00:00 A series of 5,7-disubstituted quinazolines, bearing 4-heteroaryl substituents such as 2-pyridinylamine or 2-pyrazinylamine, has been synthetised and evaluated as c-Src kinase inhibitors 16203139

名称对应

Type IDs
Gene
UniProtKB-ID: CSK_RAT
UniprotKB: P32577
UniParc: UPI00001132C9
EMBL: X58631, BC098863
Ensembl: ENSRNOG00000019374
KO: rno:315707
Nucleutide sequences
EMBL-CDS: AAH98863.1, CAA41484.1
Ensembl_TRS: ENSRNOT00000026358, ENSRNOT00000091223
Protein sequencees
Ensembl_PRO: ENSRNOP00000068638, ENSRNOP00000026358
RefSeq: XP_006243225.1, NP_001025210.1, XP_006243226.1
Others
UniRef100: UniRef100_P32577
UniRef90: UniRef90_P32577
UniRef50: UniRef50_P32577
UniGene: Rn.2759

全选

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研究热度

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