| Type | Description |
|---|---|
| Definition | leucine rich repeat and Ig domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-30 11:53:00 | LINGO-1 siRNA nanoparticles silencing promoted central remyelination in ethidium bromide-induced demyelination in rats. | 30759305 |
| 2018-09-01 10:09:00 | in both immature and adult brains, Lingo-1 signaling plays important roles in seizure-induced damage to myelin sheaths and axon growth | 29383653 |
| 2017-08-19 10:13:00 | Myelin loss and subsequent axon degeneration contributes to a variety of neurological diseases, such as multiple sclerosis (MS). | 28193690 |
| 2016-10-22 11:16:00 | We propose that LINGO-1 functions as a negative feedback regulator of signaling by cognate receptor tyrosine kinases including TrkA, TrkB and TrkC. | 26546150 |
| 2016-07-16 10:11:00 | LINGO-1-RNA interference-treated neural stem cell transplantation increased tissue repair and functional recovery of the injured spinal cord in rats. | 26491860 |
| Type | IDs |
|---|---|
| Synonymous | Lrrn6a |
| Gene |
UniProtKB-ID:
G3V881_RAT,
Q562A6_RAT
UniprotKB:
G3V881,
Q562A6
UniParc:
UPI000050565A,
UPI0000358141
EMBL:
CH473975,
BC092632,
AABR07070243
Ensembl:
ENSRNOG00000017193
KO:
rno:315691
|
| Nucleutide sequences |
EMBL-CDS:
EDL95583.1,
AAH92632.1
Gene_ORFName:
rCG_57832
Ensembl_TRS:
ENSRNOT00000023084
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000023084
RefSeq:
XP_017451138.1,
XP_017451137.1,
XP_006243182.1,
XP_017451135.1,
XP_017451134.1,
XP_017451136.1,
NP_001094192.1,
XP_017451133.1,
XP_008764492.1
|
| Others |
UniRef100:
UniRef100_A0A1U8BQR3,
UniRef100_A9DA50
UniRef90:
UniRef90_Q96FE5
UniRef50:
UniRef50_Q96FE5
UniGene:
Rn.20269
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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