| Type | Description |
|---|---|
| Definition | Topoisomerase 3beta |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 11:48:00 | Top3beta interacts biochemically and genetically with the silencing complex (RISC) containing AGO2, p68 RNA helicase, and FMRP. | 30470739 |
| 2018-01-27 10:59:00 | These results demonstrate that TDRD3 can enhance the biochemical activities of Top3beta on both DNA and RNA substrates, in addition to its function of targeting Top3beta to critical sites in subcellular compartments. | 27582462 |
| 2013-11-16 11:09:00 | The results of this study suggested that Top3beta acts as an RNA topoisomerase and works with FMRP to promote the expression of mRNAs that are crucial for synapse formation. | 23912945 |
| 2010-01-21 00:00:00 | studies suggest that the topo III enzyme behaves as a structure-specific endonuclease in vivo, providing a reversible DNA cleavage activity that is specific for unpaired regions in the DNA | 12048241 |
| Type | IDs |
|---|---|
| Synonymous | CG3458, Dmel\CG3458, TOP3, Top3, Topo IIIbeta, dTop3beta, top3, top3[beta], top3beta, topo III[beta] |
| Gene |
UniProtKB-ID:
TOP3B_DROME,
X2JEB4_DROME
UniprotKB:
O96651,
X2JEB4
UniParc:
UPI0000124A13
EMBL:
AE014298,
BT016116,
AF099909
EnsemblGenome:
FBgn0026015
KO:
dme:Dmel_CG3458
|
| Nucleutide sequences |
EMBL-CDS:
AAF46144.1,
AAV37001.1,
AAD13219.1,
AHN59409.1
Gene_ORFName:
CG3458,
CG3458,
Dmel_CG3458
EnsemblGenome_TRS:
FBtr0340028,
FBtr0070930,
FBtr0070930,
FBtr0340028
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0309042,
FBpp0070891,
FBpp0070891,
FBpp0309042
RefSeq:
NP_511059.2,
NP_001284938.1
|
| Others |
UniRef100:
UniRef100_O96651
UniRef90:
UniRef90_O96651
UniRef50:
UniRef50_O96651
UniGene:
Dm.2946
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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