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3151 HMGN2

3151

HMGN2

high mobility group nucleosomal binding domain 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition high mobility group nucleosomal binding domain 2

研究结论

Date Results Publications
2020-09-19 16:26:00 High-mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis. 31699896
2020-04-11 12:29:00 Urinary tract infection is one of the most common bacterial infections which is mainly caused by Escherichia coli (UPEC). HMGN2 expression is elevated in bladder epithelial cell line 5637 (BEC 5637). HMGN2 induces autophagy in BEC 5637 via AMPK/ULK1 pathway. Viable UPEC J96 suppresses autophagy in BEC 5637. HMGN2 boosts UPEC J96 proliferation in BEC 5637. 30952427
2019-09-14 10:54:00 This study suggests that HMGN2 is an antitumor effector molecule of gammadeltaT cells. 29401165
2018-04-28 10:02:00 these results uncover a novel link between nuclear protein HMGN2 and Nrf2-mediated cellular redox circumstance and suggest roles of HMGN2 in autonomous immune response to Pseudomonas aeruginosa infection 28408162
2017-10-21 12:34:00 HMGN1 and HMGN2 remodel core and linker histone tail domains within chromatin. 28973435

名称对应

Type IDs
Synonymous HMG17
Gene
UniProtKB-ID: HMGN2_HUMAN
UniprotKB: P05204
UniParc: UPI000013EBD7
EMBL: X13546, BC075837, BC081567, BC070297, M12623, BC110390, BC072011, BC072010, AL513365, BC014644, BC071707, BC032140, BC003050, BC000378, CR542122
Ensembl: ENSG00000198830
KO: hsa:3151
Nucleutide sequences
EMBL-CDS: AAH00378.1, CAG46919.1, AAA52678.1, AAH32140.2, AAH14644.2, AAH72011.1, CAA31898.1, AAH70297.1, AAH72010.1, AAH71707.1, AAI10391.1, AAH03050.1, AAH81567.1, AAH75837.1
Ensembl_TRS: ENST00000619352, ENST00000361427
Protein sequencees
Ensembl_PRO: ENSP00000481160, ENSP00000355228
RefSeq: NP_005508.1
Others
UniRef100: UniRef100_P05204
UniRef90: UniRef90_P05204
UniRef50: UniRef50_P05204
UniGene: Hs.181163
CCDS: CCDS283.1

全选

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研究热度

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