| Type | Description |
|---|---|
| Definition | fibroblast growth factor receptor substrate 2 |
| Date | Results | Publications |
|---|---|---|
| 2010-09-20 11:57:00 | the activation of FRS2alpha by FGL was significantly lower than the activation by FGF1, indicating a differential signaling profile induced by NCAM compared with the cognate growth factor | 20175207 |
| 2010-01-21 00:00:00 | The interaction of FRS2 beta with Rho family GTPase 1 (Rnd1) suppresses the inhibitory effect of Rnd1 on RhoA. | 15738000 |
| 2010-01-21 00:00:00 | a dual mechanism where deletion of the 770YXXL773 motif promotes FGFR2 IIIb C3 transforming activity by causing aberrant receptor recycling and stability and persistent FRS2-dependent signaling. | 19103595 |
| 2010-01-21 00:00:00 | A functional role for Shc and likely FRS2 in ALK-dependant MAP-kinase activation and neuronal differentiation of PC12 cells. | 17274988 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
D4A244_RAT
UniprotKB:
D4A244
UniParc:
UPI0000182A39
EMBL:
AABR07057201,
AABR07057200,
CH473960
Ensembl:
ENSRNOG00000005642
KO:
rno:314850
|
| Nucleutide sequences |
EMBL-CDS:
EDM16633.1
Gene_ORFName:
rCG_48891
Ensembl_TRS:
ENSRNOT00000007472
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000007472
RefSeq:
NP_001101567.2,
XP_006241443.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JZZ5
UniRef90:
UniRef90_Q8C180
UniRef50:
UniRef50_Q8C180
UniGene:
Rn.22182
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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