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31429 ovo

31429

ovo

ovo

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition ovo

研究结论

Date Results Publications
2020-04-04 12:58:00 Here, the authors show that a molecular complex identified in Drosophila epidermal differentiation, comprising Mlpt peptides, ubiquitin-ligase Ubr3 and transcription factor Shavenbaby (Svb), represents an ancient developmental module required for early insect embryo patterning. 30896406
2020-02-22 11:49:00 Transcription sites of the full svb cis-regulatory region inserted into a different chromosome colocalized with the svb locus, increasing Ubx concentration, the transcriptional output of svb, and partially rescuing the phenotype. 31294690
2019-01-05 11:32:00 Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis 30504772
2017-09-23 13:08:00 Co-expressing ectopic SoxN with svb rescued diverse denticle morphologies. Conversely, removing SoxN activity eliminated the residual denticles found in svb mutant embryos. Furthermore, several known Svb target genes are also activated by SoxN, and we have discovered two novel target genes of SoxN that are expressed in denticle-producing cells and that are regulated independently of Svb. 28506986
2017-06-24 12:36:00 Report the high-resolution functional dissection of a robust enhancer of the shavenbaby gene that has contributed to morphological evolution. We found that robustness is encoded by many binding sites for the transcriptional activator Arrowhead and that, during evolution, some of these activator sites were lost, weakening enhancer activity. 27840106

名称对应

Type IDs
Synonymous CG15467, CG6824, Dmel\CG6824, Fs(1)K1103, Fs(1)K1237, Fs(1)K155, OVO, Ovo, Ovo-D, Shv, Svb, Svb/Ovo, fs(1)K1237, fs(1)M1, fs(1)M38, ovo/shavenbaby, ovo/svb, ovoD, svb
Gene
UniProtKB-ID: OVO_DROME
UniprotKB: P51521
UniParc: UPI0000124AAA, UPI000007F318, UPI000007F9F9, UPI0000078C75
EMBL: AJ430589, AY119649, X59772, U11383, AY094838, AJ430588, S83520, AE014298
EnsemblGenome: FBgn0003028
KO: dme:Dmel_CG6824
Nucleutide sequences
EMBL-CDS: AAB50919.1, AAM50303.1, CAD23207.1, AAF46001.2, AAB50918.1, CAB36921.1, AAF46003.2, AAB60216.1, ABC67174.1, CAD23206.1, AAF46002.2, ACZ95210.1, AAM11191.1
Gene_ORFName: CG6824
EnsemblGenome_TRS: FBtr0070740, FBtr0301914, FBtr0100408, FBtr0070739, FBtr0070738
Protein sequencees
EnsemblGenome_PRO: FBpp0070706, FBpp0070708, FBpp0070707, FBpp0099822, FBpp0291128
RefSeq: NP_726972.1, NP_001162673.1, NP_525077.2, NP_726971.1, NP_001033831.1
Others
UniRef100: UniRef100_P51521
UniRef90: UniRef90_P51521
UniRef50: UniRef50_P51521
UniGene: Dm.1677

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