| Type | Description |
|---|---|
| Definition | VAMP-associated protein 33kDa |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 12:35:00 | VAP proteins (VAPs) mediate ER to Golgi tethering and their loss may affect phosphatidylinositol-4-phosphate (PtdIns4P) transfer between these organelles. Loss of VAPs elevates PtdIns4P levels in the Golgi, leading to an expansion of the endosomal pool derived from the Golgi. | 30741620 |
| 2019-10-12 10:06:00 | Lgl promoted the activity of the V-ATPase by interacting with Vap33 (VAMP-associated protein of 33 kDa). Vap33 physically and genetically interacted with Lgl and V-ATPase subunits and repressed V-ATPase-mediated endosomal vesicle acidification and Notch signaling. | 29871910 |
| 2019-08-17 10:14:00 | an interesting interplay between SOD1, and mTOR signalling that regulates the dynamics of VAP aggregation, is reported. | 30635270 |
| 2016-01-02 11:55:00 | the relationship between DVAP-P58 phenotypes and the Drosophila modifiers, raises the possibility that pharmacological manipulation of these genes may assist in developing treatments to ameliorate or prevent ALS-related abnormalities | 25826266 |
| 2013-02-23 10:32:00 | We propose that Vap function is required in neurons to selectively traffic proteins to axons, and disruption of this function may contribute to the pathology of ALS. | 23197716 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:GM03307, CG5014, DVAP, DVAP-33A, DVAP33A, Dmel\CG5014, VAP, VAP-33, VAP-33-1, VAP33-A, VAPB, Vap-33-1, Vap-33A, Vap33-1, anon-EST:Liang-2.42, anon-WO03040301.124, clone 2.42, dVAP, dVAP33A, dvap, dvap33a, l(1)G0231, vap-33A, vap33-1 |
| Gene |
UniProtKB-ID:
Q9W4N8_DROME,
Q7KVX5_DROME
UniprotKB:
Q9W4N8,
Q7KVX5
UniParc:
UPI00001E284C,
UPI0000082073
EMBL:
AE014298,
AY060395
EnsemblGenome:
FBgn0029687
KO:
dme:Dmel_CG5014
|
| Nucleutide sequences |
EMBL-CDS:
AAL25434.1,
AAS72339.1,
AAF45909.1,
AAS72341.2,
AAS72340.1
Gene_ORFName:
CG5014,
Dmel_CG5014,
Dmel_CG5014,
CG5014
EnsemblGenome_TRS:
FBtr0070618,
FBtr0342739,
FBtr0070616,
FBtr0070617
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0089170,
FBpp0309607,
FBpp0070589,
FBpp0089169
RefSeq:
NP_570087.1,
NP_996347.1,
NP_996348.1,
NP_996346.2
|
| Others |
UniRef100:
UniRef100_Q7KVX5,
UniRef100_Q9W4N8
UniRef90:
UniRef90_Q9W4N8
UniRef50:
UniRef50_Q9W4N8
UniGene:
Dm.4003
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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