| Type | Description |
|---|---|
| Definition | epidermal growth factor receptor pathway substrate 15 |
| Date | Results | Publications |
|---|---|---|
| 2015-01-24 10:08:00 | Knockdown of Eps15 suppresses the internalization of GluA1 but not the mutant GluA1 that lacks ubiquitination sites, indicating a role of Eps15 for the internalization of ubiquitinated AMPARs | 25023288 |
| 2011-12-10 10:51:00 | distinct forms of Eps15 direct EGFR to either the late endosome/lysosome for degradation (Eps15) or to the recycling endosome for transit back to the cell surface (Eps15S) | 21832070 |
| 2011-11-26 11:25:00 | FCHO2 regulates clathrin-mediated endocytosis through its interactions with membranes and Eps15. | 21762413 |
| 2010-01-21 12:36:00 | Nedd4-mediated ubiquitination of Cx43 is required to recruit Eps15, through its ubiquitin-interacting motif, and targets ubiquitinated Cx43 to the endocytic pathway. | 19835873 |
| 2010-01-21 00:00:00 | Eps15 plays an important role in clathrin-coated vesicle formation not only at the plasma membrane but also at the TGN during the secretory process | 18524853 |
| Type | IDs |
|---|---|
| Synonymous | RGD1307641 |
| Gene |
UniProtKB-ID:
Q5JC29_RAT
UniprotKB:
Q5JC29
UniParc:
UPI000049EBE9
EMBL:
AY190609
KO:
rno:313474
|
| Nucleutide sequences |
EMBL-CDS:
AAP12671.1
|
| Protein sequencees |
RefSeq:
NP_001352319.1,
NP_001009424.1
|
| Others |
UniRef100:
UniRef100_Q5JC29
UniRef90:
UniRef90_E9PSY8
UniRef50:
UniRef50_P42567
UniGene:
Rn.22316
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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